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Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors.
Philip, Charles-André; Laskov, Ido; Beauchamp, Marie-Claude; Marques, Maud; Amin, Oreekha; Bitharas, Joanna; Kessous, Roy; Kogan, Liron; Baloch, Tahira; Gotlieb, Walter H; Yasmeen, Amber.
Affiliation
  • Philip CA; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
  • Laskov I; Division of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
  • Beauchamp MC; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
  • Marques M; Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
  • Amin O; Division of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
  • Bitharas J; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
  • Kessous R; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
  • Kogan L; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
  • Baloch T; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
  • Gotlieb WH; Division of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
  • Yasmeen A; Segal Cancer Center, Lady Davis Institute of Medical Research, McGill University, 3755 Cote Ste. Catherine Road, Montreal, QC, H3T 1E2, Canada.
BMC Cancer ; 17(1): 638, 2017 Sep 08.
Article in En | MEDLINE | ID: mdl-28886696
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endometrial Neoplasms / Phosphatidylinositol 3-Kinases / PTEN Phosphohydrolase / Rad51 Recombinase / Poly(ADP-ribose) Polymerase Inhibitors Limits: Female / Humans Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Canada Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endometrial Neoplasms / Phosphatidylinositol 3-Kinases / PTEN Phosphohydrolase / Rad51 Recombinase / Poly(ADP-ribose) Polymerase Inhibitors Limits: Female / Humans Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Canada Country of publication: United kingdom