A novel ceftazidime/avibactam, rifabutin, tedizolid and moxifloxacin (CARTM) regimen for pulmonary Mycobacterium avium disease.

Deshpande, Devyani; Srivastava, Shashikant; Pasipanodya, Jotam G; Lee, Pooi S; Gumbo, Tawanda

Deshpande, Devyani; Srivastava, Shashikant; Pasipanodya, Jotam G; Lee, Pooi S; Gumbo, Tawanda.

Affiliation

Deshpande D; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, TX, USA.
Srivastava S; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, TX, USA.
Pasipanodya JG; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, TX, USA.
Lee PS; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, TX, USA.
Gumbo T; Center for Infectious Diseases Research and Experimental Therapeutics, Baylor Research Institute, Baylor University Medical Center, Dallas, TX, USA.

J Antimicrob Chemother ; 72(suppl_2): i48-i53, 2017 Sep 01.

Article in En | MEDLINE | ID: mdl-28922809

Subject(s)

Anti-Bacterial Agents/pharmacology; Lung Diseases/drug therapy; Models, Biological; Mycobacterium avium Complex/drug effects; Mycobacterium avium-intracellulare Infection/drug therapy; Anti-Bacterial Agents/administration & dosage; Azabicyclo Compounds/administration & dosage; Azabicyclo Compounds/pharmacology; Ceftazidime/administration & dosage; Ceftazidime/pharmacology; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Fluoroquinolones/administration & dosage; Fluoroquinolones/pharmacology; Humans; Lung Diseases/microbiology; Macrophages/microbiology; Microbial Sensitivity Tests; Moxifloxacin; Organophosphates/administration & dosage; Organophosphates/pharmacology; Oxazoles/administration & dosage; Oxazoles/pharmacology; Rifabutin/administration & dosage; Rifabutin/pharmacology; THP-1 Cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mycobacterium avium Complex / Mycobacterium avium-intracellulare Infection / Lung Diseases / Anti-Bacterial Agents / Models, Biological Limits: Humans Language: En Journal: J Antimicrob Chemother Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom

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