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Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
Giaime, Emilie; Tong, Youren; Wagner, Lisa K; Yuan, Yang; Huang, Guodong; Shen, Jie.
Affiliation
  • Giaime E; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Tong Y; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Wagner LK; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Yuan Y; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Huang G; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Shen J; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Program in Neuroscience, Harvard Medical School, Boston, MA 02115, USA. Electronic address: jshen@bwh.harvard.edu.
Neuron ; 96(4): 796-807.e6, 2017 Nov 15.
Article in En | MEDLINE | ID: mdl-29056298
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Aging / Protein Serine-Threonine Kinases / Dopaminergic Neurons / Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / Nerve Degeneration Limits: Animals Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Aging / Protein Serine-Threonine Kinases / Dopaminergic Neurons / Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / Nerve Degeneration Limits: Animals Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States