Oseltamivir-resistant influenza A(H1N1)pdm09 virus associated with high case fatality, India 2015.

Tandel, Kundan; Sharma, Shashi; Dash, Paban Kumar; Parida, ManMohan

Tandel, Kundan; Sharma, Shashi; Dash, Paban Kumar; Parida, ManMohan.

Affiliation

Tandel K; Division of Virology, Defence R&D Establishment (DRDE), Gwalior, MP, India.
Sharma S; Division of Virology, Defence R&D Establishment (DRDE), Gwalior, MP, India.
Dash PK; Division of Virology, Defence R&D Establishment (DRDE), Gwalior, MP, India.
Parida M; Division of Virology, Defence R&D Establishment (DRDE), Gwalior, MP, India.

J Med Virol ; 90(5): 836-843, 2018 05.

Article in En | MEDLINE | ID: mdl-29288584

Subject(s)

Antiviral Agents/pharmacology; Drug Resistance, Viral; Influenza A Virus, H1N1 Subtype/drug effects; Influenza A Virus, H1N1 Subtype/isolation & purification; Influenza, Human/mortality; Influenza, Human/virology; Oseltamivir/pharmacology; Adult; Aged; Amino Acid Substitution; Disease Outbreaks; Female; Genotype; Humans; India/epidemiology; Influenza, Human/epidemiology; Male; Middle Aged; Mortality; Mutation, Missense; Neuraminidase/genetics; Polymorphism, Restriction Fragment Length; RNA, Viral/genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Viral Proteins/genetics; Young Adult

Key words

genetic variation; influenza virus; mutation/mutation rate; neuraminidase inhibitor; pandemics, resistance

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Drug Resistance, Viral / Influenza, Human / Influenza A Virus, H1N1 Subtype / Oseltamivir Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: J Med Virol Year: 2018 Document type: Article Affiliation country: India Country of publication: United States

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