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BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.
Li, Xiangyi; Baek, GuemHee; Ramanand, Susmita G; Sharp, Adam; Gao, Yunpeng; Yuan, Wei; Welti, Jon; Rodrigues, Daniel N; Dolling, David; Figueiredo, Ines; Sumanasuriya, Semini; Crespo, Mateus; Aslam, Adam; Li, Rui; Yin, Yi; Mukherjee, Bipasha; Kanchwala, Mohammed; Hughes, Ashley M; Halsey, Wendy S; Chiang, Cheng-Ming; Xing, Chao; Raj, Ganesh V; Burma, Sandeep; de Bono, Johann; Mani, Ram S.
Affiliation
  • Li X; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Baek G; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Ramanand SG; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Sharp A; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Gao Y; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Yuan W; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Welti J; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Rodrigues DN; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Dolling D; Clinical Trials and Statistics Unit, Institute of Cancer Research, London SM2 5NG, UK.
  • Figueiredo I; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Sumanasuriya S; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Crespo M; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Aslam A; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Li R; Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Yin Y; Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Mukherjee B; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Kanchwala M; Eugene McDermott Center for Human Growth & Development, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Hughes AM; Target Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Halsey WS; Target Sciences, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Chiang CM; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Xing C; Eugene McDermott Center for Human Growth & Development, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Raj GV; Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Burma S; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • de Bono J; Prostate Cancer Targeted Therapy and Cancer Biomarkers Group, Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Mani RS; Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA; Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: ram.mani@utsouthwest
Cell Rep ; 22(3): 796-808, 2018 01 16.
Article in En | MEDLINE | ID: mdl-29346775

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Transcription Factors / Nuclear Proteins / Oncogene Proteins, Fusion / DNA End-Joining Repair Limits: Humans / Male Language: En Journal: Cell Rep Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Transcription Factors / Nuclear Proteins / Oncogene Proteins, Fusion / DNA End-Joining Repair Limits: Humans / Male Language: En Journal: Cell Rep Year: 2018 Document type: Article Affiliation country: United States Country of publication: United States