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Design, synthesis and identification of silicon-containing HCV NS5A inhibitors with pan-genotype activity.
Liu, Baomin; Gai, Kuo; Qin, Hui; Liu, Xushi; Cao, Yuan; Lu, Qin; Lu, Dandan; Chen, Deyang; Shen, Hengqiao; Song, Wei; Zhang, Yang; Wang, Xiaojin; Xu, Hongjiang; Zhang, Yinsheng.
Affiliation
  • Liu B; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Gai K; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Qin H; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Liu X; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Cao Y; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Lu Q; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Lu D; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Chen D; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Shen H; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Song W; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Zhang Y; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Wang X; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Xu H; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China.
  • Zhang Y; Chia Tai Tianqing Pharmaceutical Group Co., LTD, Jiangsu Key Laboratory of Antiviral Drug Research, 699-8 Xuanwu Ave. Building #9, Nanjing 210023, Jiangsu Province, China. Electronic address: zys@cttq.com.
Eur J Med Chem ; 148: 95-105, 2018 Mar 25.
Article in En | MEDLINE | ID: mdl-29454920
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silicon / Viral Nonstructural Proteins / Hepacivirus / Enzyme Inhibitors Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Med Chem Year: 2018 Document type: Article Affiliation country: China Country of publication: France
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silicon / Viral Nonstructural Proteins / Hepacivirus / Enzyme Inhibitors Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Med Chem Year: 2018 Document type: Article Affiliation country: China Country of publication: France