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Structural modeling identifies Plasmodium vivax 4-diphosphocytidyl-2C-methyl-d-erythritol kinase (IspE) as a plausible new antimalarial drug target.
Kadian, Kavita; Vijay, Sonam; Gupta, Yash; Rawal, Ritu; Singh, Jagbir; Anvikar, Anup; Pande, Veena; Sharma, Arun.
Affiliation
  • Kadian K; Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India.
  • Vijay S; Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India.
  • Gupta Y; Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India.
  • Rawal R; Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India.
  • Singh J; Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India.
  • Anvikar A; Epidemiology and Clinical Research, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India.
  • Pande V; Department of Biotechnology, Kumaun University, Nainital, Uttarakhand, India.
  • Sharma A; Protein Biochemistry and Structural Biology Laboratory, National Institute of Malaria Research (ICMR), Sector-8, Dwarka, New Delhi, India. Electronic address: arushar@gmail.com.
Parasitol Int ; 67(4): 375-385, 2018 Aug.
Article in En | MEDLINE | ID: mdl-29550587
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium vivax / Drug Delivery Systems / Erythritol / Models, Structural / Antimalarials Limits: Humans Country/Region as subject: Asia Language: En Journal: Parasitol Int Journal subject: PARASITOLOGIA Year: 2018 Document type: Article Affiliation country: India Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium vivax / Drug Delivery Systems / Erythritol / Models, Structural / Antimalarials Limits: Humans Country/Region as subject: Asia Language: En Journal: Parasitol Int Journal subject: PARASITOLOGIA Year: 2018 Document type: Article Affiliation country: India Country of publication: Netherlands