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Pharmacokinetic-Pharmacodynamic Modeling in Pediatric Drug Development, and the Importance of Standardized Scaling of Clearance.
Germovsek, Eva; Barker, Charlotte I S; Sharland, Mike; Standing, Joseph F.
Affiliation
  • Germovsek E; Infection, Inflammation and Rheumatology Section, UCL Great Ormond Street Institute of Child Heath, University College London, London, UK. eva.germovsek@farmbio.uu.se.
  • Barker CIS; Pharmacometrics Research Group, Department of Pharmaceutical Biosciences, Uppsala University, PO Box 591, 751 24, Uppsala, Sweden. eva.germovsek@farmbio.uu.se.
  • Sharland M; Infection, Inflammation and Rheumatology Section, UCL Great Ormond Street Institute of Child Heath, University College London, London, UK.
  • Standing JF; Paediatric Infectious Diseases Research Group, Institute for Infection and Immunity, St George's, University of London, London, UK.
Clin Pharmacokinet ; 58(1): 39-52, 2019 01.
Article in En | MEDLINE | ID: mdl-29675639
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmacokinetics / Pharmacological and Toxicological Phenomena / Drug Development / Models, Biological Type of study: Guideline / Prognostic_studies Limits: Child / Humans Language: En Journal: Clin Pharmacokinet Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmacokinetics / Pharmacological and Toxicological Phenomena / Drug Development / Models, Biological Type of study: Guideline / Prognostic_studies Limits: Child / Humans Language: En Journal: Clin Pharmacokinet Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland