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Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer.
Moses, Michael A; Kim, Yeong Sang; Rivera-Marquez, Genesis M; Oshima, Nobu; Watson, Matthew J; Beebe, Kristin E; Wells, Catherine; Lee, Sunmin; Zuehlke, Abbey D; Shao, Hao; Bingman, William E; Kumar, Vineet; Malhotra, Sanjay V; Weigel, Nancy L; Gestwicki, Jason E; Trepel, Jane B; Neckers, Leonard M.
Affiliation
  • Moses MA; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Kim YS; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Rivera-Marquez GM; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Oshima N; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Watson MJ; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Beebe KE; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Wells C; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Lee S; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Zuehlke AD; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Shao H; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, California.
  • Bingman WE; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
  • Kumar V; Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University School of Medicine, Stanford, California.
  • Malhotra SV; Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University School of Medicine, Stanford, California.
  • Weigel NL; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
  • Gestwicki JE; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, California.
  • Trepel JB; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.
  • Neckers LM; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland. neckersl@mail.nih.gov.
Cancer Res ; 78(14): 4022-4035, 2018 07 15.
Article in En | MEDLINE | ID: mdl-29764864
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Androgen / Molecular Chaperones / HSP70 Heat-Shock Proteins / HSP40 Heat-Shock Proteins / Prostatic Neoplasms, Castration-Resistant / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Res Year: 2018 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Androgen / Molecular Chaperones / HSP70 Heat-Shock Proteins / HSP40 Heat-Shock Proteins / Prostatic Neoplasms, Castration-Resistant / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Res Year: 2018 Document type: Article Country of publication: United States