Evaluating clinical and laboratory effects of ozone in non-surgical periodontal treatment: a randomized controlled trial
J. appl. oral sci
; 27: e20180108, 2019. tab, graf
Artículo
en Inglés
| LILACS, BBO - Odontología
| ID: biblio-975873
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract Objective:
This study aims to evaluate the clinical and biochemical (oxidative stress and pro-inflammatory mediators) effects of the gaseous ozone use accompanied by scaling and root planning (SRP) in periodontal treatment. Material andMethods:
The study population consisted of 40 patients with chronic periodontitis (CP) randomly sorted into two groups of 20. The experimental group received SRP plus 3 watts gaseous ozone in two separate applications five days apart, whereas the control group received SRP plus placebo. Clinical periodontal parameters were assayed and saliva samples were taken before the initial and one month after the second treatment. Periodontal examination assessed plaque index (PI), gingival index (GI), probing depth, and clinical attachment level (CAL). Total antioxidant status (TAS), total oxidant status (TOS), nitric oxide (NO), 8-hydroxy-2'-deoxyguanosine (8-OHdG), myeloperoxidase (MPO), glutathione (GSH), malondialdehyde (MDA), and transforming growth factor-beta (TGF-β) levels were evaluated from saliva samples.Results:
Changes following treatment in PI, GI, probing depth, and CAL scores were similar for both groups (p>0.05). Of note, TGF-β levels were observed to be higher in the treatment group than in controls (p<0.05). Changes in 8-OHdG, TAS, TOS, NO, MPO, GSH and MDA levels, however, were not significantly different between groups (p>0.05).Conclusion:
The findings of this study indicate that SRP plus gaseous ozone versus SRP alone does not correlate to a significant improvement in periodontal recovery.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Contexto en salud:
Agenda de Salud Sostenible para las Américas
Problema de salud:
Objetivo 9: Enfermedades no transmisibles y salud mental
Base de datos:
BBO - Odontología
/
LILACS
Asunto principal:
Oxidantes Fotoquímicos
/
Ozono
/
Aplanamiento de la Raíz
/
Periodontitis Crónica
Tipo de estudio:
Ensayo clínico controlado
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
J. appl. oral sci
Asunto de la revista:
Odontología
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
İnonu University/TR
/
Canakkale Onsekiz Mart University/TR
/
Firat University/TR
/
Yildirim Beyazit University/TR