Risk factor differences in acute myocardial infarction between young and older people: a systematic review and meta-analysis / Diferenças de fatores de risco no infarto agudo do miocárdio entre jovens e idosos: uma revisão sistemática e metanálise
Int. j. cardiovasc. sci. (Impr.)
; 32(2): 163-176, mar.-abr. 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-988222
Biblioteca responsable:
BR44.1
Ubicación: BR44.1
ABSTRACT
Acute myocardial infarction (AMI) is less frequent in young individuals (≤ 45 years) than in older ones (> 45 years). Young AMI patients differ from older AMI patients in different ways. This article aims to assess the differences between young and older AMI patients. A search was made in the database of Cochrane Library, PubMed, BioMed Central and Embase, sence their establishment to December 2016, using the key words risk factors, clinical characteristics, acute myocardial infarction and young. Meta-analysis was performed by using the Review Manager 5.3 software, pooled odds ratios and 95% confidence intervals were used to assess the strength of differences. Eight studies with fairly quality, enrolling 13,358 patients in the analysis. Compared with older AMI patients, young AMI patients had a higher rate of smoking and obesity (OR = 2.71,95%CI1.87 to 3.92; OR = 1.76,95%CI1.13 to 2.74), higher rate of family history of coronary artery disease and alcohol consumption (OR = 2.36,95%CI1.22 to 4.59; OR = 1.76,95%CI1.04 to 2.97). Moreover, Young AMI patients had a lower rate of hypertension and diabetes mellitus (OR = 0.52,95%CI0.37 to 0.73; OR = 0.58,95%CI0.50 to 0.67). No significant differences were observed in hyperlipidemia, a subgroup data-analysis showed a higher total cholesterol, triglyceride lipase, and low-density lipoprotein levels (p < 0.05), and lower levels of high-density lipoprotein (p < 0.01) in young AMI patients. Smoking, family history of coronary artery disease, obesity and alcohol consumption are the most main risk factors of AMI among young individuals, and young AMI patients have better prognosis than older ones
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
LILACS
Asunto principal:
Factores de Riesgo
/
Infarto del Miocardio
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
/
Revisión sistemática
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Int. j. cardiovasc. sci. (Impr.)
Asunto de la revista:
Cardiología
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Renmin Hospital of Wuhan University/CN