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Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center
Tang, Shiying; Hao, Han; Fang, Dong; Zheng, Wei; Ge, Peng; Su, Xiaohong; He, Qun; Yang, Xinyu; Shen, Qi; Li, Xuesong; Yu, Wei; Lin, Jian; Zhou, Liqun.
Afiliação
  • Tang, Shiying; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Hao, Han; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Fang, Dong; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Zheng, Wei; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Ge, Peng; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Su, Xiaohong; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • He, Qun; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Yang, Xinyu; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Shen, Qi; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Li, Xuesong; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Yu, Wei; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Lin, Jian; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
  • Zhou, Liqun; Peking University. Institute of Urology. Department of Urology, National Urological Cancer Center. Beijing. CN
Int. braz. j. urol ; 44(2): 258-266, Mar.-Apr. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-892980
Biblioteca responsável: BR1.1
ABSTRACT
ABSTRACT Purpose To investigate the incidence and pathologic characteristics of prostate cancer (PCa) incidentally discovered at the time of radical cystectomy and its impact on overall survival. Materials and Methods A single center retrospective study of 762 male patients who underwent radical cystoprostatectomy from Jan 1994 to Dec 2012. Results Of all included patients, 132 (17.3%) were found to have PCa. Patients with incidental PCa had a significantly higher mean age (69.2 vs. 62.2 years, P=0.015). Among the 132 patients with PCa, prostate specific antigen (PSA) analysis was available in 76 patients (57.6%), with a median value of 1.06ng/mL, and 61 (80.3%) patients had a PSA value below 4ng/mL. Four hundred and thirty-six patients (57.1%) were successfully followed, with a median duration of 46.5 months. The overall 5-year survival rate was 62.1%, and the 5-year cancer-specific survival rate was 72%. PCa recurrence was defined by two consecutive PSA values of >0.2 ng/mL and rising, and no PCa recurrence occurred. According to a univariate analyses, incidental PCa was not associated with cancer-specific survival (P=0.192) or overall survival (P=0.493). According to univariate analyses, the overall survival of patients with PCa was not associated with prostate cancer staging, PSA value, or Gleason score (All P values>0.05). Conclusions Prostate cancer incidentally discovered at the time of radical cystectomy does not decrease overall survival. Patients with incidental PCa were older than those without. The PSA value before operation is not helpful for predicting incidental prostate cancers.
Assuntos


Texto completo: Disponível Coleções: Bases de dados internacionais Contexto em Saúde: Agenda de Saúde Sustentável para as Américas / ODS3 - Saúde e Bem-Estar / ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis Problema de saúde: Objetivo 9: Redução de doenças não transmissíveis / Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis / Neoplasia da Bexiga / Neoplasia da Próstata Base de dados: LILACS Assunto principal: Neoplasias da Próstata / Neoplasias da Bexiga Urinária / Achados Incidentais Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adulto / Idoso / Idoso, 80 anos ou mais / Humanos / Masculino Idioma: Inglês Revista: Int. braz. j. urol Assunto da revista: Urologia Ano de publicação: 2018 Tipo de documento: Artigo País de afiliação: China Instituição/País de afiliação: Peking University/CN

Texto completo: Disponível Coleções: Bases de dados internacionais Contexto em Saúde: Agenda de Saúde Sustentável para as Américas / ODS3 - Saúde e Bem-Estar / ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis Problema de saúde: Objetivo 9: Redução de doenças não transmissíveis / Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis / Neoplasia da Bexiga / Neoplasia da Próstata Base de dados: LILACS Assunto principal: Neoplasias da Próstata / Neoplasias da Bexiga Urinária / Achados Incidentais Tipo de estudo: Estudo diagnóstico / Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adulto / Idoso / Idoso, 80 anos ou mais / Humanos / Masculino Idioma: Inglês Revista: Int. braz. j. urol Assunto da revista: Urologia Ano de publicação: 2018 Tipo de documento: Artigo País de afiliação: China Instituição/País de afiliação: Peking University/CN
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