What do Cochrane systematic reviews say about the use of cannabinoids in clinical practice?
São Paulo med. j
; 136(5): 472-478, Sept.-Oct. 2018. tab
Artigo
em Inglês
| LILACS
| ID: biblio-979377
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND:
The therapeutic effects of cannabinoid compounds have been the center of many investigations. This study provides a synthesis on all Cochrane systematic reviews (SRs) that assessed the use of cannabinoids as a therapeutic approach. DESIGN ANDSETTING:
Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).METHODS:
A broad search was conducted in the Cochrane Database of Systematic Reviews to retrieve any Cochrane SRs that assessed the efficacy and safety of cannabinoids as a therapeutic approach. The results and key characteristics of all reviews included were summarized and discussed.RESULTS:
Eight SRs were included. They assessed the use of cannabinoids for the following types of conditions neurological (two SRs), psychiatric (two SRs), rheumatological (one SR), infectious (one SR) and oncological (two SRs). There was moderate-quality evidence showing that the use of cannabinoids reduced nausea and vomiting among adults, compared with placebo. Additionally, there was moderate-quality evidence showing that there was no difference between cannabinoids and prochlorperazine regarding the number of participants who reported vomiting, in this same population.CONCLUSIONS:
This review identified eight Cochrane systematic reviews that provided evidence of unknown to moderate quality regarding the use of cannabinoids as a therapeutic intervention. Further studies are still imperative for solid conclusions to be reached regarding practical recommendations.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
/
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.5 Prevenção e tratamento do consumo de substâncias psicoativas
Problema de saúde:
Objetivo 7: Evidência e conhecimento em matéria de saúde
/
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Transtornos por Uso de Cannabis
/
Transtornos por Uso de Cocaina e Outros Estimulantes
Base de dados:
LILACS
Assunto principal:
Canabinoides
/
Revisões Sistemáticas como Assunto
Tipo de estudo:
Ensaio clínico controlado
/
Guia de prática clínica
/
Estudo prognóstico
/
Revisão sistemática
Limite:
Humanos
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal de São Paulo/BR
/
Universidade Metropolitana de Santos/BR