Osteonecrosis de los maxilares asociada a bifosfonatos / No disponible

RESUMEN

En los últimos años, en la literatura se han recogido diversas series de osteoquimionecrosis asociadas a bifosfonatos. En algunos pacientes que tomaban bifosfonatos se observó dolor, exposición ósea y osteitis tras una exodoncia u espontáneamente. Presentamos nuestra experiencia desde nuestro servicio de cirugía oral y maxilofacial en el seguimiento de 15 pacientes que han presentado esta patología, incluyendo nuestro protocolo diagnóstico-terapéutico (AU)

ABSTRACT

Recently in the literature many papers concerning bone osteonecrosis of the jaws (BON) have appeared related with Biphosphonates. Some of the patients taking Biphosphonates developped oral lesions which are similar in appearance to those of radiation-induced osteonecrosis. Clinically, they appear as ragged oral mucosal ulcerations that expose underlying bone and often are extremely painful, many times related with previous manipulation and sometimes spontaneously. The lesions are persistent and do not respond to conventional treatment modalities. We present our experience and recommendations which are based on expert opinion from the literature, the guidelines for the diagnoses and management of care of patients who develop BON; the prevention of this complication based on current knowledge; and recommendations for the routine dental treatment of patients receiving bisphosphonate therapy (AU)