Analise dos fatores de risco da doença vascular do enxerto em pacientes assintomáticos após transplante cardíaco / Analysis of the risk factors for allograft vasculopathy in asymptomatic patients after cardiac transplantation
Arq. bras. cardiol
; 75(5): 413-28, Nov. 2000.
Artigo
em Português, Inglês
| LILACS
| ID: lil-273497
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
To study the influence of immune and nonimmune risk factors on the development of allograft vasculopathy after cardiac transplantation.METHODS:
We studied 39 patients with a mean age of 46 + or - 12 years. The following variables were analyzed weight (kg), body mass index (kg/m²), donor's age and sex, rejection episodes in the first and second years after transplantation, systolic and diastolic blood pressures (mmHg), total cholesterol and fractions (mg/dL), triglycerides (mg/dL), diabetes, and cytomegalovirus infection. The presence of allograft vasculopathy was established through coronary angiography.RESULTS:
Allograft vasculopathy was observed in 15 (38 percent) patients. No statistically significant difference was observed between the two groups in regard to hypertension, cytomegalovirus infection, diabetes, donor's sex and age, rejection episodes in the first and second years after transplantation, and cholesterol levels. We observed a tendency toward higher levels of triglycerides in the group with disease. Univariate and multivariate analyses showed statistically significant differences between the two groups when we analyzed the body mass index (24.53 + or - 4.3 versus 28.11 + or - 4.6; p=0.019).CONCLUSION:
Body mass index was an important marker of allograft vasculopathy in the population studied
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Transplante de Coração
/
Doença das Coronárias
/
Rejeição de Enxerto
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Adolescente
/
Adulto
/
Idoso, 80 anos ou mais
/
Criança
/
Feminino
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
/
Português
Revista:
Arq. bras. cardiol
Assunto da revista:
Cardiologia
Ano de publicação:
2000
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de São Paulo/BR