Terapêutica farmacológica do infarto do miocárdio em idosos. Análise de oito anos / Pharmacological therapy for myocardial infarction in the elderly. An 8-year analysis
Arq. bras. cardiol
; 78(4): 364-373, Apr. 2002. tab
Artigo
em Português, Inglês
| LILACS
| ID: lil-306440
Biblioteca responsável:
BR1.1
RESUMO
OBJECTIVE:
To assess the changes in the medicamentous treatment of elderly patients hospitalized with acute myocardial infarction occurring over an 8-year period.METHODS:
We retrospectively analyzed 379 patients above the age of 65 years with acute myocardial infarction who were admitted to the coronary unit of a university-affiliated hospital from 1990 to 1997. The patients were divided into 2 groups, according to the period of time of hospital admission as follows group 1 - from 1990 to 1993; and group 2 - from 1994 to 1997.RESULTS:
The use of beta-blockers (40.8 percentchi 75.2 percent, p<0.0001) and angiotensin-converting enzyme inhibitors (42 percent chi59.5 percent, p=0.001) was significantly greater in group 2, while the use of calcium antagonists (42 percent chi 18.5 percent, p<0.0001) and general antiarrhythmic drugs (19.1 percent chi 10.8 percent, p=0.03) was significantly lower. No significant difference was observed in regard to the use of acetylsalicylic acid, thrombolytic agents, nitrate, and digitalis in the period studied. The length of hospitalization was shorter in group 2 (13.4±8.9 days chi 10.5±7.5 days, p<0.001). The in-hospital mortality was 35.7 percent in group 1 and 26.6 percent in group 2 (p=0.07).CONCLUSION:
Significant changes were observed in the treatment of elderly patients with acute myocardial infarction, with a greater use of beta-blockers and angiotensin-converting enzyme inhibitors and a lower use of calcium antagonists and antiarrhythmic drugs in group 2. The length of hospitalization and the mortality rate were also lower in group 2, even though the reduction in mortality was not statistically significant
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Doença Cardiovascular
/
Doença Isquêmica do Coração
Base de dados:
LILACS
Assunto principal:
Infarto do Miocárdio
Tipo de estudo:
Estudo observacional
Limite:
Idoso
/
Idoso, 80 anos ou mais
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
/
Português
Revista:
Arq. bras. cardiol
Assunto da revista:
Cardiologia
Ano de publicação:
2002
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal de Säo Paulo/BR