Exercise for depression in older adults: a meta-analysis of randomized controlled trials adjusting for publication bias
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 38(3): 247-254, July-Sept. 2016. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-792752
Biblioteca responsável:
BR1.1
ABSTRACT
Objective:
To evaluate the antidepressant effects of exercise in older adults, using randomized controlled trial (RCT) data.Methods:
We conducted a meta-analysis of exercise in older adults, addressing limitations of previous works. RCTs of exercise interventions in older people with depression (≥ 60 years) comparing exercise vs. control were eligible. A random-effects meta-analysis calculating the standardized mean difference (SMD) (95% confidence interval [95%CI]), meta-regressions, and trim, fill, and fail-safe number analyses were conducted.Results:
Eight RCTs were included, representing 138 participants in exercise arms and 129 controls. Exercise had a large and significant effect on depression (SMD = -0.90 [95%CI -0.29 to -1.51]), with a fail-safe number of 71 studies. Significant effects were found for 1) mixed aerobic and anaerobic interventions, 2) at moderate intensity, 3) that were group-based, 4) that utilized mixed supervised and unsupervised formats, and 5) in people without other clinical comorbidities.Conclusion:
Adjusting for publication bias increased the beneficial effects of exercise in three subgroup analysis, suggesting that previous meta-analyses have underestimated the benefits of exercise due to publication bias. We advocate that exercise be considered as a routine component of the management of depression in older adults.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
Problema de saúde:
Objetivo 9: Redução de doenças não transmissíveis
Base de dados:
LILACS
Assunto principal:
Ensaios Clínicos Controlados Aleatórios como Assunto
/
Transtorno Depressivo Maior
/
Terapia por Exercício
Tipo de estudo:
Ensaio clínico controlado
/
Estudo de etiologia
/
Fatores de risco
/
Revisão sistemática
Limite:
Idoso
/
Idoso, 80 anos ou mais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Assunto da revista:
Psiquiatria
Ano de publicação:
2016
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Federal do Rio Grande do Sul/BR