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Precision Medicine in Inflammatory Bowel Diseases.

Clin Pharmacol Ther; 102(4): 623-632, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28699158

Resumo

Inflammatory bowel diseases (IBDs) are a lifelong condition of chronic, recurrent inflammation in the gut. The introduction of immunomodulators and biologic agents markedly improved the treatment of IBDs. Therefore, the use of biologics became an essential element in the rational therapy of IBDs. Various substances are currently evaluated in clinical trials, addressing different target structures and offering further approaches in the field of IBD. Regarding the growing number of treatment options, the need for prediction of therapy response became a necessity and is the subject of the present research.