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Fluorescent Probes for Detection of Protein: From Bench to Bed.

Protein Pept Lett; 2018 05 30.
Artigo em Inglês | MEDLINE | ID: mdl-29848256
It is important to quantitatively detect specific analytes for varieties of applications ranging from life sciences to environmental monitoring. Proteins play vital roles in the life system, especially for the evaluation of many diseases. Thus, the quantitative measurement of protein is beneficial for the diagnosis and monitoring of diseases. Among the sensing methods currently developed, fluorescence detection is of particular concern as a technique with the potential to provide accurate and quantitative analyses. A wide variety of molecular probes for protein detection have been designed and synthesized for sensing, imaging, and biomedical applications. In this report highlight, we provide an overview of the varied probes from small molecular to nanoparticle-based sensors that have been applied to detect a various proteins from bench to bed. Furthermore, some emerging trends, future directions as well as challenges in this rapidly growing field are discussed.