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Is there an association between dipeptidyl peptidase-4 inhibitors and autoimmune disease? A population-based study.

Immunol Res; 2018 May 31.
Artigo em Inglês | MEDLINE | ID: mdl-29855994
The association of dipeptidyl peptidase-4 inhibitors (DPP4is) with autoimmune diseases is controversial. While these agents were proposed as a novel therapeutic approach for several inflammatory diseases by blocking T cell proliferation and cytokine production, they were found to trigger inflammatroy bowel disease, inflammatory arthritis and bullous pemphigoid. Our objective is to examine the association between DPP4i and autoimmune diseases. This study was conducted as a cross-sectional study u