Social determinants of prostate cancer in the Caribbean: A systematic review and meta-analysis

The University of the West IndiesBrown, CR; The University of the West IndiesHercules, SM; The University of the West IndiesSobers-Grannum, N; The University of the West IndiesMurphy, MM; The University of the West IndiesUnwin, N; The University of the West IndiesHowitt, C; The University of the West IndiesAlvarado; The University of the West IndiesHambleton, IR

The University of the West IndiesBrown, CR; The University of the West IndiesHercules, SM; The University of the West IndiesSobers-Grannum, N; The University of the West IndiesMurphy, MM; The University of the West IndiesUnwin, N; The University of the West IndiesHowitt, C; The University of the West IndiesAlvarado; The University of the West IndiesHambleton, IR.

Afiliação

The University of the West IndiesBrown, CR; The University of the West IndiesBrown, CR. St. Michael. Barbados
The University of the West IndiesHercules, SM; The University of the West IndiesHercules, SM. St. Michael. Barbados
The University of the West IndiesSobers-Grannum, N; The University of the West IndiesSobers-Grannum, N. St. Michael. Barbados
The University of the West IndiesMurphy, MM; The University of the West IndiesMurphy, MM. St. Michael. Barbados
The University of the West IndiesUnwin, N; The University of the West IndiesUnwin, N. St. Michael. Barbados
The University of the West IndiesHowitt, C; The University of the West IndiesHowitt, C. St. Michael. Barbados
The University of the West IndiesAlvarado; The University of the West IndiesAlvarado. St. Michael. Barbados
The University of the West IndiesHambleton, IR; The University of the West IndiesHambleton, IR. St. Michael. Barbados

West Indian med. j ; 65(Supp. 3): 56-57, 2016.

Artigo em Inglês | MedCarib | ID: med-18104

Biblioteca responsável: TT2.1

Localização: TT5; W1, WE389

ABSTRACT

ABSTRACT

OBJECTIVE:

To determine what is known of the distribution by social determinants of health of the risk factors,occurrence and outcomes of prostate cancer among Caribbean populations. DESIGN AND

METHODS:

MEDLINE, EMBASE, SciELO,CINAHL, CUMED, LILACS and IBECS were searched for observational studies examining social determinants and dietary calcium, disease incidence/prevalence and disease stage/grade/recurrence/survival/mortality. Caribbean studies published from 20042014 with samples > 50 were eligible. Independent reviewing and data abstraction was conducted according to STROBE and Cochrane guidelines. Random-effects meta-analyses were conducted.

FINDINGS:

From 444 unique citations, 15 articles from 12 studies were included, of which five were appropriate for meta-analysis. Weak evidence showed higher dietary calcium in higher socio-economic position (SEP) and urban-dwelling children; prostate cancer incidence was higher in men of African descent and men with less education, and mortality was higher in men with less education, rural-dwelling men and men of lower SEP. Two meta-analyses showed that men with primary or less education were more likely to have prostate cancer (OR1.50, 95%CI 1.14, 1.96, I2 0%) and married men were less likely to have prostate cancer (OR 0.67, 95%CI 0.45, 0.99,I2 0%).

CONCLUSIONS:

Caribbean men of lower SEP were found to have a higher incidence and mortality from prostate cancer. Further work is needed to address potential confounding, particularly between ethnicity and other social determinants, and whether case fatality differs by SEP, such as through later diagnosis and poorer access to healthcare. This paper provides a benchmark for future research into social determinants of prostate cancer in the Caribbean.

Assuntos

Humanos; Masculino; Neoplasias da Próstata; Metanálise; Fatores de Risco; Região do Caribe

Buscar no Google

Adicionar na Minha BVS

Imprimir

XML

Coleções: Bases de dados internacionais Contexto em Saúde: ODS3 - Saúde e Bem-Estar Problema de saúde: Meta 3.8 Atingir a cobertura universal de saúde Base de dados: MedCarib Assunto principal: Neoplasias da Próstata / Fatores de Risco / Metanálise / Região do Caribe Tipo de estudo: Estudo de etiologia / Guia de prática clínica / Estudo observacional / Fatores de risco / Revisão sistemática Aspecto: Determinantes sociais da saúde Limite: Humanos / Masculino Idioma: Inglês Revista: West Indian med. j Ano de publicação: 2016 Tipo de documento: Artigo / Congresso e conferência Instituição/País de afiliação: The University of the West IndiesAlvarado/Barbados / The University of the West IndiesBrown, CR/Barbados / The University of the West IndiesHambleton, IR/Barbados / The University of the West IndiesHercules, SM/Barbados / The University of the West IndiesHowitt, C/Barbados / The University of the West IndiesMurphy, MM/Barbados / The University of the West IndiesSobers-Grannum, N/Barbados / The University of the West IndiesUnwin, N/Barbados

Buscar no Google

Adicionar na Minha BVS

Imprimir

XML