Existence of a silent gene for pseudocholinesterase in a Trinidad population
West Indian med. j
; 43(4): 140-2, Dec. 1994.
Artigo
em Inglês
| MedCarib
| ID: med-7684
Biblioteca responsável:
JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
Although the values reported were higher than those reported for Caucasians, differences in dibucaine number for pseudocholinesterase values among the three ethnic groups in Trinidad and Tobago, were not significant. Eight individuals had intermediate dibucaine numbers values between 40 and 70; one of them was African, 3 were East Indians, and 4 Mixed. Two of the mixed group were of Portuguese lineage and had significantly lower dibucaine numbers and enzyme concentration. Two sisters of East Indian origin had an inestimable dibucaine number and their pseudocholinesterase values were just detectable, suggesting the presence of a 'silent gene' for pseudocholinesterase. These studies, which are being extended, suggest that the dibucaine number should be estimated prior to succinylcholine administration in patients in Trinidad and Tobago who are at risk of apnoea (AU)
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Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Butirilcolinesterase
/
Dibucaína
Limite:
Adolescente
/
Adulto
/
Idoso
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Caribe Inglês
/
Trinidad e Tobago
Idioma:
Inglês
Revista:
West Indian med. j
Ano de publicação:
1994
Tipo de documento:
Artigo