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Risk and timing of clinical events according to diabetic status of patients treated with everolimus-eluting bioresorbable vascular scaffolds versus everolimus-eluting stent: 2-year results from a propensity score matched comparison of ABSORB EXTEND and SPIRIT trials
Campos, Carlos M; Caixeta, Adriano; Franken, Marcelo; Bartorelli, Antonio L; Whitbourn, Robert J; Wu, Chiung‐Jen; Kao, Hsien Li Pau; Rosli, Mohd Ali; Carrie, Didier; De Bruyne, Bernard; Stone, Gregg W; Serruys, Patrick W; Abizaid, Alexandre.
Afiliação
  • Campos, Carlos M; Department of Cardiology, Hospital Israelita Albert Einstein. São Paulo. BR
  • Caixeta, Adriano; Department of Cardiology, Hospital Israelita Albert Einstein. São Paulo. BR
  • Franken, Marcelo; Department of Cardiology, Hospital Israelita Albert Einstein. São Paulo. BR
  • Bartorelli, Antonio L; Centro Cardiologico Monzino, IRCCS. Milan. IT
  • Whitbourn, Robert J; Department of Cardiology, St Vincent's Hospital. Victoria. AU
  • Wu, Chiung‐Jen; Department of Cardiology, Chang Gung Memorial Hospital. Niao-Sung Hsiang. TW
  • Kao, Hsien Li Pau; Department of Cardiology, National Taiwan University Hospital. Taipei. TW
  • Rosli, Mohd Ali; Department of Cardiology, Institute Jantung Negara. Kuala Lumpur. MY
  • Carrie, Didier; Department of Cardiology, Hôpital de Rangueil CHU. Toulouse. FR
  • De Bruyne, Bernard; Department of Cardiology, Cardiovascular Center Aalst. Aalst. BE
  • Stone, Gregg W; Department of Interventional Cardiology, Columbia University Medical Center. New York. US
  • Serruys, Patrick W; International Centre for Circulatory Health, NHLI, Imperial College London. London. GB
  • Abizaid, Alexandre; Instituto Dante Pazzanese de Cardiologia. São Paulo. BR
Catheter Cardiovasc Interv ; 91(3): 387-395, 2018. tab, graf
Artigo em Inglês | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1061866
Biblioteca responsável: BR79.1
Localização: BR79.1
ABSTRACT

OBJECTIVES:

to compare the occurrence of clinical events in diabetics treated with the Absorb bioresorbable vascular scaffold (Absorb BVS; Abbott Vascular, Santa Clara, CA) versus everolimus-eluting metal stents (EES; XIENCE V; Abbott Vascular, Santa Clara, CA)

BACKGROUND:

There are limited data dedicated to clinical outcomes of diabetic patients treated with bioresorbable scaffolds (BRS) at 2-year horizon.

METHODS:

The present study included 812 patients in the ABSORB EXTEND study in which a total of 215 diabetic patients were treated with Absorb BVS. In addition, 882 diabetic patients treated with EES in pooled data from the SPIRIT clinical program (SPIRIT II, SPIRIT III and SPIRIT IV trials) were used for comparison by applying propensity score matching using 29 different variables. The primary endpoint was ischemia driven major adverse cardiac events (ID-MACE), including cardiac death, myocardial infarction (MI), and ischemia driven target lesion revascularization (ID-TLR).

RESULTS:

After 2 years, the ID-MACE rate was 6.5% in the Absorb BVS vs. 8.9% in the Xience group (P = 0.40). There was no difference for MACE components or definite/probable device thrombosis (HR 1.43 [0.24,8.58]; P = 0.69). The occurrence of MACE was not different for both diabetic status (insulin- and non-insulin-requiring diabetes) in all time points up to the 2-year follow-up for the Absorb and Xience groups...
Assuntos
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Coleções: Bases de dados nacionais / Brasil Base de dados: Sec. Est. Saúde SP / SESSP-IDPCPROD Assunto principal: Stents / Stents Farmacológicos / Coração Tipo de estudo: Estudo de etiologia / Fatores de risco Idioma: Inglês Revista: Catheter Cardiovasc Interv Ano de publicação: 2018 Tipo de documento: Artigo Instituição/País de afiliação: Centro Cardiologico Monzino, IRCCS/IT / Department of Cardiology, Cardiovascular Center Aalst/BE / Department of Cardiology, Chang Gung Memorial Hospital/TW / Department of Cardiology, Hospital Israelita Albert Einstein/BR / Department of Cardiology, Hôpital de Rangueil CHU/FR / Department of Cardiology, Institute Jantung Negara/MY / Department of Cardiology, National Taiwan University Hospital/TW / Department of Cardiology, St Vincent's Hospital/AU / Department of Interventional Cardiology, Columbia University Medical Center/US / Instituto Dante Pazzanese de Cardiologia/BR
Buscar no Google
Coleções: Bases de dados nacionais / Brasil Base de dados: Sec. Est. Saúde SP / SESSP-IDPCPROD Assunto principal: Stents / Stents Farmacológicos / Coração Tipo de estudo: Estudo de etiologia / Fatores de risco Idioma: Inglês Revista: Catheter Cardiovasc Interv Ano de publicação: 2018 Tipo de documento: Artigo Instituição/País de afiliação: Centro Cardiologico Monzino, IRCCS/IT / Department of Cardiology, Cardiovascular Center Aalst/BE / Department of Cardiology, Chang Gung Memorial Hospital/TW / Department of Cardiology, Hospital Israelita Albert Einstein/BR / Department of Cardiology, Hôpital de Rangueil CHU/FR / Department of Cardiology, Institute Jantung Negara/MY / Department of Cardiology, National Taiwan University Hospital/TW / Department of Cardiology, St Vincent's Hospital/AU / Department of Interventional Cardiology, Columbia University Medical Center/US / Instituto Dante Pazzanese de Cardiologia/BR
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