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Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study
Dehghan, Mahshid; Mente, Andrew; Zhang, Xiaohe; Swaminathan, Sumathi; Li, Wei; Mohan, Viswanathan; Iqba, Romaina; Kumar, Rajesh; Wentzel-Viljoen, Edelweiss; Rosengren, Annika; Amma, Leela Itty; Avezum, Alvaro; Chifamba, Jephat; Diaz, Rafael; Khatib, Rasha; Lear, Scott; Lopez-Jaramillo, Patricio; Liu, Xiaoyun; Gupta, Rajeev; Mohammadifard, Noushin; Gao, Nan; Oguz, Aytekin; Ramli, Anis Safura; Seron, Pamela; Sun, Yi; Szuba, Andrzej; Tsolekile, Lungiswa; Wielgosz, Andreas; Yusuf, Rita; Yusufali, Afzal Hussein; Teo, Koon K; Rangarajan, Sumathy; Dagenais, Gilles; Bangdiwala, Shrikant I; Islam, Shofiqul; Anand, Sonia S; Yusuf, Salim.
Afiliação
  • Dehghan, Mahshid; Population Health Research Institute, McMaster University. Hamilton. CA
  • Mente, Andrew; Population Health Research Institute, McMaster University. Hamilton. CA
  • Zhang, Xiaohe; Population Health Research Institute, McMaster University. Hamilton. CA
  • Swaminathan, Sumathi; St John's Research Institute, St John's National Academy of Health Sciences. Karnataka. IN
  • Li, Wei; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital. Beijing. CN
  • Mohan, Viswanathan; Madras Diabetes Research Foundation. Chennai. IN
  • Iqba, Romaina; Departments of Community Health Sciences and Medicine, Aga Khan University. Karachi. PK
  • Kumar, Rajesh; PGIMER School of Public Health. Chandigarh. IN
  • Wentzel-Viljoen, Edelweiss; Centre of Excellence for Nutrition, Faculty of Health Sciences, North-West University. Potchefstroom. ZA
  • Rosengren, Annika; Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg. Gothenburg. SE
  • Amma, Leela Itty; Health Action by People TC 1/1706, Medical College PO. Trivandrum. IN
  • Avezum, Alvaro; Instituto Dante Pazzanese de cardiologia. São Paulo. BR
  • Chifamba, Jephat; University of Zimbabwe, College of Health Sciences, Department of Physiology. Harare. ZW
  • Diaz, Rafael; Estudios Clínicos Latinoamérica, ECLA. Rosario. AR
  • Khatib, Rasha; Institute of Community and Public Health, Birzeit University. Birzeit. PS
  • Lear, Scott; Faculty of Health Sciences, Department of Biomedical Physiology & Kinesiology, Simon Fraser University. Burnaby. CA
  • Lopez-Jaramillo, Patricio; Fundacion Oftalmologica de Santander-FOSCAL. Floridablanca-Santander. CO
  • Liu, Xiaoyun; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital. Beijing. CN
  • Gupta, Rajeev; Eternal Heart Care Centre and Research Institute. Jaipur. IN
  • Mohammadifard, Noushin; Isfahan Cardiovascular Research Centre, Cardiovascular Research Institute, Isfahan University of Medical Sciences. Isfahan. IR
  • Gao, Nan; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital. Beijing. CN
  • Oguz, Aytekin; Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine. Istanbul. TR
  • Ramli, Anis Safura; Faculty of Medicine, Universiti Teknologi MARA. Selangor. MY
  • Seron, Pamela; Universidad de La Frontera. Temuco. CL
  • Sun, Yi; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital. Beijing. CN
  • Szuba, Andrzej; Division of Angiology, Wroclaw Medical University. Wroclaw. PL
  • Tsolekile, Lungiswa; University of the Western Cape. Cape Town. ZA
  • Wielgosz, Andreas; University of Ottawa Department of Medicine. Ottawa. CA
  • Yusuf, Rita; Independent University. Dhaka. BD
  • Yusufali, Afzal Hussein; Dubai Medical University, Hatta Hospital. Dubai. AE
  • Teo, Koon K; Population Health Research Institute, McMaster University. Hamilton. CA
  • Rangarajan, Sumathy; Population Health Research Institute, McMaster University. Hamilton. CA
  • Dagenais, Gilles; Université Laval, Institut Universitaire de Cardiologie. Québec. CA
  • Bangdiwala, Shrikant I; Population Health Research Institute, McMaster University. Hamilton. CA
  • Islam, Shofiqul; Population Health Research Institute, McMaster University. Hamilton. CA
  • Anand, Sonia S; Department of Medicine, McMaster University. Hamilton. CA
  • Yusuf, Salim; Population Health Research Institute, McMaster University. Hamilton. CA
Lancet ; 390(10107): 2050-2062, 2017.
Artigo em Inglês | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1064598
Biblioteca responsável: BR79.1
Localização: BR79.1
ABSTRACT

BACKGROUND:

The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear.

METHODS:

The Prospective Urban Rural Epidemiology (PURE) study is a large, epidemiological cohort study of individuals aged 35-70 years (enrolled between Jan 1, 2003, and March 31, 2013) in 18 countries with a median follow-up of 7·4 years (IQR 5·3-9·3). Dietary intake of 135 335 individuals was recorded using validated food frequency questionnaires. The primary outcomes were total mortality and major cardiovascular events (fatal cardiovascular disease, non-fatal myocardial infarction, stroke, and heart failure). Secondary outcomes were all myocardial infarctions, stroke, cardiovascular disease mortality, and non-cardiovascular disease mortality. Participants were categorised into quintiles of nutrient intake (carbohydrate, fats, and protein) based on percentage of energy provided by nutrients. We assessed the associations between consumption of carbohydrate, total fat, and each type of fat with cardiovascular disease and total mortality. We calculated hazard ratios (HRs) using a multivariable Cox frailty model with random intercepts to account for centre clustering...
Assuntos
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Coleções: Bases de dados nacionais / Brasil Contexto em Saúde: ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis Problema de saúde: Doença Cardiovascular Base de dados: Sec. Est. Saúde SP / SESSP-IDPCPROD Assunto principal: Carboidratos / Mortalidade / Ingestão de Alimentos / Gorduras / Cardiopatias Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Idioma: Inglês Revista: Lancet Ano de publicação: 2017 Tipo de documento: Artigo Instituição/País de afiliação: Centre of Excellence for Nutrition, Faculty of Health Sciences, North-West University/ZA / Department of Medicine, McMaster University/CA / Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg/SE / Departments of Community Health Sciences and Medicine, Aga Khan University/PK / Division of Angiology, Wroclaw Medical University/PL / Dubai Medical University, Hatta Hospital/AE / Estudios Clínicos Latinoamérica, ECLA/AR / Eternal Heart Care Centre and Research Institute/IN / Faculty of Health Sciences, Department of Biomedical Physiology & Kinesiology, Simon Fraser University/CA / Faculty of Medicine, Universiti Teknologi MARA/MY
Buscar no Google
Coleções: Bases de dados nacionais / Brasil Contexto em Saúde: ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis Problema de saúde: Doença Cardiovascular Base de dados: Sec. Est. Saúde SP / SESSP-IDPCPROD Assunto principal: Carboidratos / Mortalidade / Ingestão de Alimentos / Gorduras / Cardiopatias Tipo de estudo: Estudo de etiologia / Estudo observacional / Estudo prognóstico / Fatores de risco Idioma: Inglês Revista: Lancet Ano de publicação: 2017 Tipo de documento: Artigo Instituição/País de afiliação: Centre of Excellence for Nutrition, Faculty of Health Sciences, North-West University/ZA / Department of Medicine, McMaster University/CA / Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg/SE / Departments of Community Health Sciences and Medicine, Aga Khan University/PK / Division of Angiology, Wroclaw Medical University/PL / Dubai Medical University, Hatta Hospital/AE / Estudios Clínicos Latinoamérica, ECLA/AR / Eternal Heart Care Centre and Research Institute/IN / Faculty of Health Sciences, Department of Biomedical Physiology & Kinesiology, Simon Fraser University/CA / Faculty of Medicine, Universiti Teknologi MARA/MY
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