Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study
Lancet Diabetes Endocrinol. (Online)
; 5(10): 774-787, 2017. graf
Artigo
em Inglês
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1064536
Biblioteca responsável:
BR79.1
Localização: BR79.1
ABSTRACT
BACKGROUND:
The relation between dietary nutrients and cardiovascular disease risk markers in many regions worldwide is unknown. In this study, we investigated the effect of dietary nutrients on blood lipids and blood pressure, two of the most important risk factors for cardiovascular disease, in low-income, middle-income, and high-income countries.METHODS:
We studied 125 287 participants from 18 countries in North America, South America, Europe, Africa, and Asia in the Prospective Urban Rural Epidemiology (PURE) study. Habitual food intake was measured with validated food frequency questionnaires. We assessed the associations between nutrients (total fats, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, carbohydrates, protein, and dietary cholesterol) and cardiovascular disease risk markers using multilevel modelling. The effect of isocaloric replacement of saturated fatty acids with other fats and carbohydrates was determined overall and by levels of intakes by use of nutrient density models. We did simulation modelling in which we assumed that the effects of saturated fatty acids on cardiovascular disease events was solely related to their association through an individual risk marker, and then compared these simulated risk marker-based estimates with directly observed associations of saturated fatty acids with cardiovascular disease events.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Assunto principal:
Doenças Cardiovasculares
/
Epidemiologia
/
Lipídeos
Tipo de estudo:
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Lancet Diabetes Endocrinol. (Online)
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
Aga Khan University/PK
/
College of Health Sciences/ZW
/
Dante Pazzanese Institute of Cardiology/BR
/
Dubai Medical University/AE
/
Estudios Clinicos Latinoamerica ECLA/AR
/
Eternal Heart Care Centre and Research Institute/IN
/
Faculty of Health Sciences/CA
/
Faculty of Medicine/MY
/
Faculty of Medicine/TR
/
Fundacion Oftalmologica de Santander-FOSCAL/CO