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Resultado perinatal de un programa de reproducción asistida institucional. / [Perinatal result of an institutional assisted reproduction program].

Ochoa Rueda, Senia Suyapa; Barros Delgadillo, Juan Carlos; Paredes Chávez, Fernando Cecilio; Barroso Villa, Gerardo; Villalobos Acosta, Sergio; Sánchez Solís, Víctor; Osorio Caballero, Mauricio; Gaviño Gaviño, Fernando.
Ginecol Obstet Mex; 72: 619-27, 2004 Dec.
Artigo Espanhol | MEDLINE | ID: mdl-15813472

BACKGROUND:

Assisted reproductive technology manipulates masculine gametes, embryos and implantation. It also aids the known or unknown factor of sterility without having the base problem correction as a target. In vitro fertilization and embryo transfer are among these techniques.

OBJECTIVE:

To describe the overall outcome and the final perinatal offspring after in vitro fertilization cycle in an institutional third level hospital.

MATERIALS AND METHODS:

IVF cycles were retrospectively analyzed from October 1999 to May 2004. Several variables were described like: age, fertilization rate, implantation and pregnancy rate, fetal status, time of gestation during labor, miscarriage follicle-stimulating hormone rate and take-home baby rate. Patients underwent hypophyseal supression with GnRH analog, using a long luteal phase protocol and stimulated with recombinant FSH. Overall data is expressed as average +/- standard deviation and percentage.

RESULTS:

365 cycles were analyzed in 314 patients, average age was of 34 +/- 3.7 years, tubal factor was diagnosed in 63.3%, fertilization rate was of 60.4%, implantation rate of 37.1%, per transfer pregnancy rate of 25.1%, per transfer live born rate of 21.7%, multiple pregnancy rate of 29.3%, miscarriage rate of 28% and ectopic pregnancy rate of 4.8%. In 87.8% of the cases caesarean operation was made; multiple pregnancy offspring weighted more than 1250 g in 70% of them; 70.5% was born after 32 weeks of pregnancy; 90% was born live and with good prognosis. Glucose metabolism alterations were the most frequent maternal complication.

CONCLUSION:

Although the results obtained were similar to those of assisted reproduction centers, it suggests improving multiple pregnancy rate and abortion rate.
Selo DaSilva