Your browser doesn't support javascript.

Portal de Pesquisa da BVS

Informação e Conhecimento para a Saúde

Home > Pesquisa > ()
XML
Imprimir Exportar

Formato de exportação:

Exportar

Email
Adicionar mais destinatários
| |

Estimating the cost-effectiveness of pneumococcal conjugate vaccination in Brazil / Cálculo de la relación costo-efectividad de la vacuna conjugada antineumocócica en Brasil

Vespa, Glaucia; Constenla, Dagna O; Pepe, Camila; Safadi, Marco Aurélio; Berezin, Eitan; Moraes, José Cássio de; Campos, Carlos Alberto Herrerias de; Araujo, Denizar Vianna; Andrade, Ana Lucia S. S. de.
Rev. panam. salud pública ; 26(6): 518-528, dic. 2009. ilus, tab, graf
Artigo em Inglês | LILACS | ID: lil-536492

OBJECTIVE:

To compare the costs and benefits of pneumococcal conjugate vaccination compared with no vaccination from the perspectives of the health care system and society.

METHODS:

Using data from established sources, we estimated the incidence and mortality due to invasive pneumococcal disease, pneumonia, and acute otitis media (AOM) for a hypothetical birth cohort of children from birth to 5 years.

RESULTS:

A universal pneumococcal conjugate vaccination program was estimated capable of annually avoiding 1 047 cases of invasive disease, 58 226 cases of pneumonia, and 209 862 cases of AOM. When herd immunity effects were considered, the program prevented 1.3 million cases of pneumococcal disease and over 7 000 pneumococcal deaths. At a vaccination cost of R$ 51.12 (US$ 26.35) per dose, vaccination would cost annually R$ 4 289 (US$ 2,211) per disability-adjusted life years averted. This does not take into account herd immunity effects.

CONCLUSIONS:

At the current vaccine price, conjugate vaccination could be a cost-effective investment compared to other options to control childhood diseases. Further analysis is required to determine whether vaccination at the current price is affordable to Brazil.
Biblioteca responsável: BR1.1