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Rubella virus genotype 1G and echovirus 9 as etiologic agents of exanthematous diseases in Brazil: insights from phylogenetic analysis.

Figueiredo, Cristina Adelaide; Luchs, Adriana; Russo, Denise Hage; de Cassia Compagnoli Carmona, Rita; Afonso, Ana Maria Sardinha; de Oliveira, Maria Isabel; Curti, Suely Pires; de Moraes, José Cassio; Toscano, Cristiana M; Ciccone, Flavia Helena; Timenetsky, Maria do Carmo Sampaio Tavares.
Arch Virol; 159(6): 1445-51, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24327091
The aim of the present study was to identify the rubella virus (RV) and enterovirus (EV) genotypes detected during the Epidemiological Surveillance on Exanthematic Febrile Diseases (VIGIFEX) study and to perform phylogenetic analysis. Ten RV- and four EV-positive oropharyngeal samples isolated from cell culture were subjected to RT-PCR and sequencing. Genotype 1G and echovirus 9 (E-9) was identified in RV- and EV-positive samples, respectively. The RV 1G genotype has been persisting in Brazil since 2000-2001. No evidence of E-9 being involved in exanthematic illness in Brazil has been reported previously. Differential laboratory diagnosis is essential for management of rash and fever disease.