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Extracorporeal membrane oxygenation support in neonates: a single center experience in Turkey

Okulu, Emel; Atasay, F. Begüm; Tunç, Gaffari; Akduman, Hasan; Erdeve, Ömer; Arsan, Saadet; Eyileten, Zeynep; Uçar, Tayfun; Tutar, H. Ercan.
Turk J Med Sci; 48(2): 223-230, 2018 Apr 30.
Artigo em Inglês | MEDLINE | ID: mdl-29714432

BACKGROUND/AIM:

Extracorporeal membrane oxygenation (ECMO) is a form of life support for patients with respiratory failure, cardiac failure, or both. The aim of this study was to evaluate neonates supported with ECMO and report our experience as a Turkish neonatal intensive care unit.

MATERIALS AND METHODS:

We retrospectively reviewed 11 newborn infants treated with ECMO at Ankara University for respiratory and cardiac failure. We reported the demographic, diagnostic, laboratory, and clinical data of the patients.

RESULTS:

Eleven patients (9 male, 2 female) received ECMO support with a mean gestational age of 39.1 ± 1.6 weeks and mean birth weight of 3513 ± 506 g. Six patients received venoarterial (VA) ECMO and five patients received venovenous (VV) ECMO. Mean age at initiation and duration of ECMO was 7.2 ± 7.4 days (2­24 days) and 10.4 ± 4.9 days (5­21 days), respectively. Mean oxygenation index (OI) before ECMO was 48.5 ± 5.7. ECMO was withdrawn from one patient due to severe brain injury. The survival rate for ECMO was 73% and the survival rate to discharge was 64%, whereas the survival rate in congenital diaphragmatic hernia (CDH) cases was 40%.

CONCLUSION:

Our early results from ECMO for neonates are encouraging. Identification of patients for ECMO support and timely referral will offer a survival opportunity to complex neonatal cases.