Detalhe da pesquisa
1.
Rational design, synthesis, biological evaluation, and molecular modeling of novel naphthamide derivatives possessing potent, reversible, and competitive inhibitory mode of action over human monoamine oxidase.
Mol Divers;
2024 May 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38727994
2.
An inclusive outlook on the fate and persistence of pesticides in the environment and integrated eco-technologies for their degradation.
Toxicol Appl Pharmacol;
466: 116449, 2023 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36924898
3.
Synthesis and In Silico Study of Some New bis-[1,3,4]thiadiazolimines and bis-Thiazolimines as Potential Inhibitors for SARS-CoV-2 Main Protease.
Curr Issues Mol Biol;
44(10): 4540-4556, 2022 Sep 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36286026
4.
The comprehensive effects of aluminum oxide nanoparticles on the physiology of freshwater microalga Scenedesmus obliquus and it's phycoremediation performance for the removal of sulfacetamide.
Environ Res;
215(Pt 2): 114314, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36116497
5.
4-Anilinoquinazoline-based benzenesulfonamides as nanomolar inhibitors of carbonic anhydrase isoforms I, II, IX, and XII: design, synthesis, in-vitro, and in-silico biological studies.
J Enzyme Inhib Med Chem;
37(1): 994-1004, 2022 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35350942
6.
Synthesis, Molecular Docking Study, and Cytotoxic Activity against MCF Cells of New Thiazole-Thiophene Scaffolds.
Molecules;
27(14)2022 Jul 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35889511
7.
QSAR Modeling, Molecular Docking and Cytotoxic Evaluation for Novel Oxidovanadium(IV) Complexes as Colon Anticancer Agents.
Molecules;
27(3)2022 Jan 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35163913
8.
Design, Synthesis, Molecular Docking, and Evaluation Antioxidant and Antimicrobial Activities for Novel 3-Phenylimidazolidin-4-One and 2-Aminothiazol-4-One Derivatives.
Molecules;
27(3)2022 01 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35164032
9.
Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management.
Molecules;
27(11)2022 Jun 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35684529
10.
Synthesis, DFT calculation, pharmacological evaluation, and catalytic application in the synthesis of diverse pyrano[2,3-c]pyrazole derivatives.
Bioorg Chem;
114: 105136, 2021 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34328860
11.
Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action.
Bioorg Chem;
116: 105352, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34562673
12.
Design, Synthesis, Biological Evaluation, 2D-QSAR Modeling, and Molecular Docking Studies of Novel 1H-3-Indolyl Derivatives as Significant Antioxidants.
Int J Mol Sci;
22(19)2021 Sep 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34638734
13.
Oxazinethione Derivatives as a Precursor to Pyrazolone and Pyrimidine Derivatives: Synthesis, Biological Activities, Molecular Modeling, ADME, and Molecular Dynamics Studies.
Molecules;
26(18)2021 Sep 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34576953
14.
Computational Approaches for the Design of Novel Anticancer Compounds Based on Pyrazolo[3,4-d]pyrimidine Derivatives as TRAP1 Inhibitor.
Molecules;
26(19)2021 Sep 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34641473
15.
Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico Screening.
Molecules;
26(17)2021 Sep 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34500757
16.
DNA-Binding and Anticancer Activity of Binuclear Gold(I) Alkynyl Complexes with a Phenanthrenyl Bridging Ligand.
Molecules;
25(5)2020 Feb 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32106590
17.
DNA-Binding Capabilities and Anticancer Activities of Ruthenium(II) Cymene Complexes with (Poly)cyclic Aromatic Diamine Ligands.
Molecules;
26(1)2020 Dec 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33375289
18.
Synthesis of new class of non-sulfonamide bis-benzimidazoles as antitumor agents by inhibiting carbonic anhydrase-IX enzyme.
Int J Biol Macromol;
255: 128259, 2024 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37984572
19.
New 1,3,4-Thiadiazole Derivatives as α-Glucosidase Inhibitors: Design, Synthesis, DFT, ADME, and In Vitro Enzymatic Studies.
ACS Omega;
9(7): 7480-7490, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38405480
20.
Identification of therapeutic drug target of Shigella Flexneri serotype X through subtractive genomic approach and in-silico screening based on drug repurposing.
Infect Genet Evol;
122: 105611, 2024 May 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38823431