Detalhe da pesquisa
1.
The PI3K Pathway in Human Disease.
Cell;
170(4): 605-635, 2017 Aug 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28802037
2.
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Nature;
629(8011): 435-442, 2024 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38658751
3.
Self-eating limits EGFR-dependent tumor growth.
Cell;
154(6): 1184-6, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24034240
4.
The Pten-Parkin Axis: At the Nexus of Cancer and Neurodegeneration.
Mol Cell;
65(6): 959-960, 2017 Mar 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28306509
5.
Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity.
Proc Natl Acad Sci U S A;
116(19): 9533-9542, 2019 05 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31019077
6.
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy.
Proc Natl Acad Sci U S A;
113(1): 182-7, 2016 Jan 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26677873
7.
A metabolic (re-)balancing act.
Mol Cell;
38(4): 481-2, 2010 May 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20513422
8.
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
Mol Cell;
35(4): 442-53, 2009 Aug 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19716789
9.
The PI3K, metabolic, and autophagy networks: interactive partners in cellular health and disease.
Annu Rev Pharmacol Toxicol;
53: 89-106, 2013.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23294306
10.
Moving out: mobilizing activated T cells from lymphoid tissues.
Nat Immunol;
9(5): 455-7, 2008 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18425096
11.
The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics.
Nat Prod Rep;
30(5): 625-39, 2013 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23525375
12.
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
J Biol Chem;
285(22): 16562-71, 2010 May 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20233725
13.
Multimodal biomarker investigation on efficacy and mechanism of action for the mammalian target of rapamycin inhibitor, temsirolimus, in a preclinical mammary carcinoma OncoMouse model: a translational medicine study in support for early clinical development.
J Pharmacol Exp Ther;
339(2): 421-9, 2011 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21835932
14.
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1.
Nat Cell Biol;
5(4): 309-19, 2003 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12652307
15.
Sustained mTORC1 activity during palbociclib-induced growth arrest triggers senescence in ER+ breast cancer cells.
Cell Cycle;
20(1): 65-80, 2021 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33356791
16.
Direct control of CAR T cells through small molecule-regulated antibodies.
Nat Commun;
12(1): 710, 2021 01 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33514714
17.
Differential regulation of TCR-mediated gene transcription by Vav family members.
J Exp Med;
199(3): 429-34, 2004 Feb 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14757747
18.
Jurkat T cells and development of the T-cell receptor signalling paradigm.
Nat Rev Immunol;
4(4): 301-8, 2004 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15057788
19.
Anti-tumor immunity influences cancer cell reliance upon ATG7.
Oncoimmunology;
9(1): 1800162, 2020 08 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32923161
20.
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.
J Cell Biol;
157(2): 253-63, 2002 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11956228