Detalhe da pesquisa
1.
A maternal-effect Padi6 variant causes nuclear and cytoplasmic abnormalities in oocytes, as well as failure of epigenetic reprogramming and zygotic genome activation in embryos.
Genes Dev;
38(3-4): 131-150, 2024 Mar 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38453481
2.
Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage.
Development;
148(10)2021 05 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33999993
3.
OTX2 restricts entry to the mouse germline.
Nature;
562(7728): 595-599, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30283136
4.
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.
Development;
141(2): 377-88, 2014 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24335253
5.
Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes.
Hum Mol Genet;
23(7): 1742-53, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24234651
6.
Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition.
Development;
140(1): 43-55, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23154415
7.
The transcription factor Otx2 regulates choroid plexus development and function.
Development;
140(5): 1055-66, 2013 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23364326
8.
Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability.
Dev Biol;
373(1): 176-83, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23117062
9.
Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex.
Hum Mol Genet;
20(23): 4644-54, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21890494
10.
Identification of sixteen novel candidate genes for late onset Parkinson's disease.
Mol Neurodegener;
16(1): 35, 2021 06 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34148545
11.
Orthopedia homeodomain protein is essential for diencephalic dopaminergic neuron development.
Curr Biol;
17(10): 873-80, 2007 May 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17481897
12.
Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma.
Am J Pathol;
175(6): 2609-17, 2009 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19893048
13.
The role of Otx genes in progenitor domains of ventral midbrain.
Adv Exp Med Biol;
651: 36-46, 2009.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19731548
14.
The Otx family.
Curr Opin Genet Dev;
12(4): 409-15, 2002 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12100885
15.
Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain.
Nat Neurosci;
6(5): 453-60, 2003 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12652306
16.
Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-A.
Cell Rep;
23(12): 3635-3646, 2018 06 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29925004
17.
Otx2 controls identity and fate of glutamatergic progenitors of the thalamus by repressing GABAergic differentiation.
J Neurosci;
26(22): 5955-64, 2006 May 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16738237
18.
Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells.
Stem Cell Reports;
9(5): 1642-1659, 2017 11 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29056334
19.
Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast.
Cell Rep;
15(12): 2651-64, 2016 06 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27292645
20.
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.
Nat Commun;
7: 12589, 2016 09 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27586544