Detalhe da pesquisa
1.
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.
Cell;
145(6): 863-74, 2011 Jun 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21640374
2.
Reduced IGF-1 signaling delays age-associated proteotoxicity in mice.
Cell;
139(6): 1157-69, 2009 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20005808
3.
Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies.
J Neurosci;
38(4): 1000-1014, 2018 01 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29246926
4.
NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model.
Neurobiol Dis;
127: 390-397, 2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30928642
5.
Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease.
Neurobiol Dis;
127: 163-177, 2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30849508
6.
Corrigendum to " Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy Body Disease" [Neurobiology of Disease127 (2019) 163-177].
Neurobiol Dis;
191: 106397, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38216383
7.
Effects of single and combined immunotherapy approach targeting amyloid ß protein and α-synuclein in a dementia with Lewy bodies-like model.
Alzheimers Dement;
15(9): 1133-1148, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31378574
8.
α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease.
Hum Mol Genet;
25(6): 1100-15, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26740557
9.
Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease.
Hum Mol Genet;
25(13): 2645-2660, 2016 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27126635
10.
Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders.
Acta Neuropathol;
136(1): 69-87, 2018 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29934874
11.
Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model.
J Neurosci;
36(30): 7971-84, 2016 07 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27466341
12.
Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease.
J Biol Chem;
291(4): 1905-1920, 2016 Jan 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26620558
13.
Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy.
Neurobiol Dis;
104: 85-96, 2017 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28476636
14.
The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration.
J Neurovirol;
23(2): 290-303, 2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28105557
15.
Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies.
Neural Plast;
2017: 3851262, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28409032
16.
HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders.
J Neurosci;
35(5): 1921-38, 2015 Feb 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25653352
17.
HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders.
Neurobiol Dis;
86: 154-69, 2016 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26611103
18.
Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity.
J Neuroinflammation;
13(1): 120, 2016 05 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27220536
19.
Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.
J Neurosci;
34(28): 9441-54, 2014 Jul 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25009275
20.
A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis.
J Biol Chem;
289(25): 17917-31, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24825898