Detalhe da pesquisa
1.
Fragment-Based Discovery of Novel VE-PTP Inhibitors Using Orthogonal Biophysical Techniques.
Biochemistry;
62(14): 2161-2169, 2023 07 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37414577
2.
System truncation accelerates binding affinity calculations with the fragment molecular orbital method: A benchmark study.
J Comput Chem;
44(7): 824-831, 2023 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36444861
3.
Antiviral Activity and Resistance Profile of the Novel HIV-1 Non-Catalytic Site Integrase Inhibitor JTP-0157602.
J Virol;
96(6): e0184321, 2022 03 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35045265
4.
The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action.
Bioorg Med Chem Lett;
80: 129110, 2023 01 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36563792
5.
Fragment Molecular Orbital Based Affinity Prediction toward Pyruvate Dehydrogenase Kinases: Insights into the Charge Transfer in Hydrogen Bond Networks.
Chem Pharm Bull (Tokyo);
71(4): 299-306, 2023 Apr 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36724968
6.
Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases.
Bioorg Med Chem;
44: 116283, 2021 08 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34274549
7.
Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors.
Bioorg Med Chem;
52: 116514, 2021 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34808405
8.
Generation and cycloaddition of polymer-supported azomethine ylide via a 1,2-silatropic shift of alpha-silylimines: traceless synthesis of pyrrolidine derivatives.
Org Lett;
4(20): 3505-8, 2002 Oct 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12323055