Detalhe da pesquisa
1.
Development of certain aminoquinazoline scaffolds as potential multitarget anticancer agents with apoptotic and anti-proliferative effects: Design, synthesis and biological evaluation.
Bioorg Chem;
135: 106496, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36989735
2.
Design, synthesis and mechanistic studies of novel imidazo[1,2-a]pyridines as anticancer agents.
Bioorg Chem;
128: 106042, 2022 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35878430
3.
Design, synthesis, biological assessment, and in-Silico studies of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors.
Bioorg Chem;
121: 105687, 2022 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35196595
4.
Design, synthesis and mechanistic study of new 1,2,4-triazole derivatives as antimicrobial agents.
Bioorg Chem;
111: 104841, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33798851
5.
Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
Bioorg Chem;
116: 105394, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34619468
6.
Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers.
Bioorg Chem;
105: 104358, 2020 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33074119
7.
Design, synthesis, molecular docking and antiproliferative activity of some novel benzothiazole derivatives targeting EGFR/HER2 and TS.
Bioorg Chem;
101: 103976, 2020 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32506018
8.
Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.
Bioorg Med Chem;
24(13): 3043-3051, 2016 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27234893
9.
Ecofriendly LC-MS/MS and TLC-densitometric methods for simultaneous quantitative assay and monitoring of BEGEV regimen, in vivo pharmacokinetic study application.
Anal Methods;
15(8): 1016-1027, 2023 02 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36727667
10.
Determination of Gemcitabine and Sorafenib in Spiked Human Plasma Using Multivariate Model Update Chemometric Methods.
J AOAC Int;
106(6): 1666-1672, 2023 Nov 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37233147
11.
Determination of Bendamustine, Gemcitabine and Vinorelbine (BEGEV) regimen in spiked human plasma using multivariate model update chemometric methods.
Spectrochim Acta A Mol Biomol Spectrosc;
299: 122836, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37196550
12.
Five spectrophotometric methods for simultaneous determination of Amlodipine besylate and celecoxib in presence of its toxic impurity.
Spectrochim Acta A Mol Biomol Spectrosc;
263: 120137, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34273891
13.
Validated green chromatographic methods for determination of amlodipine and celecoxib in presence of methylacetophenone.
Bioanalysis;
13(12): 969-983, 2021 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34085866
14.
Experimentally designed chromatographic method for the simultaneous analysis of dimenhydrinate, cinnarizine and their toxic impurities.
RSC Adv;
11(3): 1450-1460, 2021 Jan 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35424104
15.
Simultaneous estimation of dimenhydrinate, cinnarizine and their toxic impurities benzophenone and diphenylmethylpiperazine; in silico toxicity profiling of impurities.
RSC Adv;
10(61): 37439-37448, 2020 Oct 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35521250
16.
Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks.
Eur J Med Chem;
205: 112662, 2020 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32763463
17.
New substituted pyrazole derivatives targeting COXs as potential safe anti-inflammatory agents.
Future Med Chem;
11(15): 1871-1882, 2019 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31517535
18.
Novel 4-methylsulfonylphenyl derivatives as NSAIDS with preferential COX-2 inhibition.
Future Med Chem;
10(1): 53-70, 2018 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29235887
19.
Anti-inflammatory indomethacin analogs endowed with preferential COX-2 inhibitory activity.
Future Med Chem;
10(21): 2521-2535, 2018 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30518260
20.
Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.
Eur J Med Chem;
150: 567-578, 2018 Apr 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29549841