Detalhe da pesquisa
1.
GATA3 (GATA-Binding Protein 3)/KMT2A (Lysine-Methyltransferase-2A) Complex by Increasing H3K4-3me (Trimethylated Lysine-4 of Histone-3) Upregulates NCX3 (Na+-Ca2+ Exchanger 3) Transcription and Contributes to Ischemic Preconditioning Neuroprotection.
Stroke;
52(11): 3680-3691, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34694864
2.
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model.
Neurobiol Dis;
159: 105480, 2021 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34411705
3.
miR-206 Reduces the Severity of Motor Neuron Degeneration in the Facial Nuclei of the Brainstem in a Mouse Model of SMA.
Mol Ther;
28(4): 1154-1166, 2020 04 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32075715
4.
Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced by Ischemic Preconditioning.
Stroke;
47(4): 1085-93, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26979866
5.
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death.
Toxicol Appl Pharmacol;
288(3): 387-98, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26307266
6.
Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage.
Mol Ther Nucleic Acids;
35(1): 102131, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38379726
7.
Metabolic rewiring and autophagy inhibition correct lysosomal storage disease in mucopolysaccharidosis IIIB.
iScience;
27(3): 108959, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38361619
8.
Stroke Causes DNA Methylation at Ncx1 Heart Promoter in the Brain Via DNMT1/MeCP2/REST Epigenetic Complex.
J Am Heart Assoc;
13(6): e030460, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38456444
9.
Phosphodiesterase 10A (PDE10A) localization in the R6/2 mouse model of Huntington's disease.
Neurobiol Dis;
52: 104-16, 2013 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23220622
10.
Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death.
Int J Biol Sci;
19(9): 2695-2710, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37324938
11.
Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice.
Biomed Pharmacother;
167: 115503, 2023 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37729728
12.
Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition.
Neurobiol Dis;
46(1): 225-33, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22311347
13.
Remote postconditioning ameliorates stroke damage by preventing let-7a and miR-143 up-regulation.
Theranostics;
10(26): 12174-12188, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33204336
14.
Sumoylation of sodium/calcium exchanger in brain ischemia and ischemic preconditioning.
Cell Calcium;
87: 102195, 2020 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32240869
15.
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage.
J Cereb Blood Flow Metab;
40(10): 2081-2097, 2020 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31696766
16.
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory.
Mol Neurobiol;
57(5): 2358-2376, 2020 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32048166
17.
Anti-miR-223-5p Ameliorates Ischemic Damage and Improves Neurological Function by Preventing NCKX2 Downregulation after Ischemia in Rats.
Mol Ther Nucleic Acids;
18: 1063-1071, 2019 Dec 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31791013
18.
Models and methods for conditioning the ischemic brain.
J Neurosci Methods;
310: 63-74, 2018 12 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30287283
19.
Acute and long-term NCX activation reduces brain injury and restores behavioral functions in mice subjected to neonatal brain ischemia.
Neuropharmacology;
135: 180-191, 2018 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29551690
20.
Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets.
Front Neurosci;
12: 510, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30131665