Detalhe da pesquisa
1.
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma.
Cell;
175(1): 101-116.e25, 2018 09 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30220459
2.
Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.
Cell;
164(3): 433-46, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26824656
3.
The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.
Cell;
161(5): 1138-1151, 2015 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25981667
4.
The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.
Mol Cell;
82(17): 3284-3298.e7, 2022 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35772404
5.
A secreted tyrosine kinase acts in the extracellular environment.
Cell;
158(5): 1033-1044, 2014 Aug 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25171405
6.
A phosphate-sensing organelle regulates phosphate and tissue homeostasis.
Nature;
617(7962): 798-806, 2023 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37138087
7.
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.
Mol Cell;
81(10): 2076-2093.e9, 2021 05 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33756106
8.
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Immunity;
50(3): 576-590.e6, 2019 03 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30770249
9.
Lin28 enhances tissue repair by reprogramming cellular metabolism.
Cell;
155(4): 778-92, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24209617
10.
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.
Cell;
155(4): 844-57, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24209622
11.
PI3K drives the de novo synthesis of coenzyme A from vitamin B5.
Nature;
608(7921): 192-198, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35896750
12.
ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.
Mol Cell;
78(6): 1178-1191.e6, 2020 06 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32485148
13.
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Cell;
149(3): 656-70, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22541435
14.
SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive.
Cell;
147(7): 1459-72, 2011 Dec 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22169038
15.
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.
Cell;
146(4): 607-20, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21854985
16.
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation.
Mol Cell;
70(5): 949-960.e4, 2018 06 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29861159
17.
Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.
Mol Cell;
70(3): 531-544.e9, 2018 05 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29727621
18.
Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function.
Mol Cell;
69(2): 279-291.e5, 2018 01 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29351847
19.
LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer.
Nature;
569(7755): 275-279, 2019 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30996345
20.
PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation.
Mol Cell;
65(6): 999-1013.e7, 2017 Mar 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28306514