Detalhe da pesquisa
1.
Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.
Cell;
177(3): 597-607.e9, 2019 04 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31002796
2.
Obesity-Associated GNAS Mutations and the Melanocortin Pathway.
N Engl J Med;
385(17): 1581-1592, 2021 10 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34614324
3.
Entrectinib-A SARS-CoV-2 Inhibitor in Human Lung Tissue (HLT) Cells.
Int J Mol Sci;
22(24)2021 Dec 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34948390
4.
A rare human variant that disrupts GPR10 signalling causes weight gain in mice.
Nat Commun;
14(1): 1450, 2023 03 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36922513
5.
Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior.
Nat Med;
28(12): 2537-2546, 2022 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36536256
6.
Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation.
Cell Rep;
34(12): 108862, 2021 03 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33761344
7.
Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases.
J Mol Biol;
425(17): 3166-77, 2013 Sep 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23806657