Detalhe da pesquisa
1.
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib.
Proc Natl Acad Sci U S A;
104(52): 20932-7, 2007 Dec 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18093943
2.
Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma.
Clin Cancer Res;
14(22): 7519-25, 2008 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19010870
3.
Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas.
PLoS Med;
4(10): e294, 2007 Oct 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17927446
4.
Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors.
Clin Cancer Res;
12(21): 6494-501, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17085664
5.
BRAF-inhibitor Associated MEK Mutations Increase RAF-Dependent and -Independent Enzymatic Activity.
Mol Cancer Res;
15(10): 1431-1444, 2017 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28655712
6.
Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor Everolimus.
Mol Cancer Ther;
14(5): 1224-35, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25724664
7.
Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
Nat Med;
21(5): 440-8, 2015 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25849130
8.
Enhanced motor function by training in spinal cord contused rats following radiation therapy.
PLoS One;
4(8): e6862, 2009 Aug 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19718437
9.
Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors.
PLoS One;
2(8): e810, 2007 Aug 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17726540