Detalhe da pesquisa
1.
DS86760016, a Leucyl-tRNA Synthetase Inhibitor with Activity against Pseudomonas aeruginosa.
Antimicrob Agents Chemother;
63(4)2019 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30670430
2.
Synthesis and evaluation of thiomannosides, potent and orally active FimH inhibitors.
Bioorg Med Chem Lett;
28(17): 2993-2997, 2018 09 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30017316
3.
Correlation of in vitro and in vivo plasma protein binding using ultracentrifugation and UPLC-tandem mass spectrometry.
Analyst;
138(20): 6106-16, 2013 Oct 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23964358
4.
Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors.
J Med Chem;
48(23): 7333-42, 2005 Nov 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16279793
5.
Preclinical drug metabolism and pharmacokinetics of salinomycin, a potential candidate for targeting human cancer stem cells.
Chem Biol Interact;
240: 146-52, 2015 Oct 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26282489
6.
Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century.
J Med Chem;
52(5): 1408-15, 2009 Mar 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19222165
7.
Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine.
J Med Chem;
52(7): 1828-44, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19284751