Detalhe da pesquisa
1.
Maintenance olaparib in patients with platinum-sensitive relapsed ovarian cancer: Outcomes by somatic and germline BRCA and other homologous recombination repair gene mutation status in the ORZORA trial.
Gynecol Oncol;
172: 121-129, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37030280
2.
Differential DNA methylation patterns of homeobox genes in proximal and distal colon epithelial cells.
Physiol Genomics;
48(4): 257-73, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26812987
3.
Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial.
J Clin Oncol;
42(5): 571-583, 2024 Feb 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37963304
4.
Impact of DNA damage repair alterations on prostate cancer progression and metastasis.
Front Oncol;
13: 1162644, 2023.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37434977
5.
Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial.
JCO Precis Oncol;
7: e2200258, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36716415
6.
Detection of BRCA1, BRCA2, and ATM Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound.
Clin Cancer Res;
29(1): 81-91, 2023 01 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36043882
7.
Homologous Recombination Repair Gene Mutation Characterization by Liquid Biopsy: A Phase II Trial of Olaparib and Abiraterone in Metastatic Castrate-Resistant Prostate Cancer.
Cancers (Basel);
13(22)2021 Nov 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34830984
8.
Genetic Alterations in the PI3K/AKT Pathway and Baseline AKT Activity Define AKT Inhibitor Sensitivity in Breast Cancer Patient-derived Xenografts.
Clin Cancer Res;
26(14): 3720-3731, 2020 07 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32220884
9.
Capivasertib, an AKT Kinase Inhibitor, as Monotherapy or in Combination with Fulvestrant in Patients with AKT1 E17K-Mutant, ER-Positive Metastatic Breast Cancer.
Clin Cancer Res;
26(15): 3947-3957, 2020 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32312891
10.
Inflammation-associated DNA methylation patterns in epithelium of ulcerative colitis.
Epigenetics;
12(8): 591-606, 2017 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28557546