RESUMO
We isolated arenavirus RNA from white-toothed woodrats (Neotoma leucodon) captured in a region of Mexico in which woodrats are food for humans. Analyses of nucleotide and amino acid sequence data indicated that the woodrats were infected with a novel Tacaribe serocomplex virus, proposed name Real de Catorce virus.
Assuntos
Infecções por Arenaviridae/veterinária , Arenavirus do Novo Mundo , Doenças dos Roedores/virologia , Animais , Anticorpos Antivirais/análise , Infecções por Arenaviridae/epidemiologia , Infecções por Arenaviridae/imunologia , Infecções por Arenaviridae/virologia , Arenavirus do Novo Mundo/genética , Arenavirus do Novo Mundo/isolamento & purificação , Genoma Viral , Rim/imunologia , Rim/virologia , México/epidemiologia , Filogenia , RNA Viral/genética , RNA Viral/isolamento & purificação , Doenças dos Roedores/epidemiologia , Doenças dos Roedores/imunologia , Roedores , Análise de Sequência de RNA , Baço/imunologia , Baço/virologiaRESUMO
Blood samples from 4893 cricetid rodents were tested for antibody (immunoglobulin G) to Whitewater Arroyo virus and Amaparí virus to extend our knowledge of the natural host range and geographical distribution of Tacaribe serocomplex viruses in North America. Antibodies to arenaviruses were found in northern pygmy mice (Baiomys taylori), woodrats (Neotoma spp.), northern grasshopper mice (Onychomys leucogaster), oryzomys (Oryzomys spp.), deermice (Megadontomys nelsoni and Peromyscus spp.), harvest mice (Reithrodontomys spp.), and cotton rats (Sigmodon spp.) captured in New Mexico, Texas, or Mexico. Comparison of endpoint antibody titers to Whitewater Arroyo virus and Amaparí virus in individual blood samples indicated that the Tacaribe complex viruses enzootic in Texas and Mexico are antigenically diverse.