Detalhe da pesquisa
1.
Spinocerebellar ataxia 38: structure-function analysis shows ELOVL5 G230V is proteotoxic, conformationally altered and a mutational hotspot.
Hum Genet;
142(8): 1055-1076, 2023 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37199746
2.
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia.
Brain;
144(12): 3710-3726, 2021 12 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34972208
3.
NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk.
J Neurosci;
40(4): 932-941, 2020 01 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31811028
4.
Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology.
Int J Mol Sci;
22(14)2021 Jul 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34298918
5.
Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and Aß1-42-mediated toxicity.
Neurobiol Dis;
140: 104849, 2020 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32222473
6.
A case report of late-onset cerebellar ataxia associated with a rare p.R342W TGM6 (SCA35) mutation.
BMC Neurol;
20(1): 408, 2020 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33160304
7.
Mutations in TGM6 induce the unfolded protein response in SCA35.
Hum Mol Genet;
26(19): 3749-3762, 2017 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28934387
8.
Transglutaminases, neuronal cell death and neural repair: implications for traumatic brain injury and therapeutics.
Curr Opin Neurol;
32(6): 796-801, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31577602
9.
Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.
J Neurosci;
37(6): 1413-1427, 2017 02 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28011744
10.
Nitration of Hsp90 induces cell death.
Proc Natl Acad Sci U S A;
110(12): E1102-11, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23487751
11.
Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition.
J Neurosci;
34(43): 14328-37, 2014 Oct 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25339746
12.
Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosis.
J Biol Chem;
288(22): 15699-711, 2013 May 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23592792
13.
International Society for Extracellular Vesicles Workshop. QuantitatEVs: multiscale analyses, from bulk to single extracellular vesicle.
J Extracell Biol;
3(1)2024 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38405579
14.
Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.
J Neurosci;
32(19): 6561-9, 2012 May 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22573678
15.
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.
J Neurosci Res;
91(8): 1066-75, 2013 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23456821
16.
Protein biomarkers for the diagnosis and prognosis of Amyotrophic Lateral Sclerosis.
Neurosci Res;
197: 31-41, 2023 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37689321
17.
Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscle.
Curr Opin Pharmacol;
71: 102394, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37463556
18.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Nat Commun;
14(1): 603, 2023 02 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36746939
19.
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function.
Sci Adv;
9(1): eade1694, 2023 01 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36608116
20.
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle.
Nat Commun;
14(1): 602, 2023 02 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36746942