Detalhe da pesquisa
1.
Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's.
Eur J Neurosci;
59(6): 1242-1259, 2024 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37941514
2.
The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.
Blood;
136(21): 2410-2415, 2020 11 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32599615
3.
Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Proc Natl Acad Sci U S A;
116(7): 2545-2550, 2019 02 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30683716
4.
Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro.
Molecules;
26(21)2021 Nov 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34771052
5.
Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family.
Bioorg Med Chem;
28(22): 115724, 2020 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33128909
6.
Anthelmintic drug discovery: target identification, screening methods and the role of open science.
Beilstein J Org Chem;
16: 1203-1224, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32550933
7.
A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor.
J Pharmacol Exp Ther;
361(3): 417-428, 2017 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28360334
8.
Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Bioorg Med Chem;
25(9): 2657-2665, 2017 05 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28341403
9.
Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists.
Bioorg Med Chem;
23(1): 241-63, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25487422
10.
Development of Highly Potent, G-Protein Pathway Biased, Selective, and Orally Bioavailable GPR84 Agonists.
J Med Chem;
67(1): 110-137, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38146625
11.
Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84.
Eur J Pharmacol;
956: 175960, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37543157
12.
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines.
Eur J Med Chem;
258: 115509, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37343464
13.
Osmium-free direct syn-dihydroxylation of alkenes.
Chem Soc Rev;
40(1): 114-28, 2011 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21049111
14.
A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2.
Sci Adv;
7(15)2021 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33837087
15.
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni.
ACS Infect Dis;
7(5): 1260-1274, 2021 05 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33797218
16.
NMR waterLOGSY as An Assay in Drug Development Programmes for Detecting Protein-Ligand Interactions-NMR waterLOGSY.
Bio Protoc;
10(13): e3666, 2020 Jul 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33659336
17.
20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?
DNA Cell Biol;
39(11): 1926-1937, 2020 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33001759
18.
Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells.
ACS Appl Bio Mater;
3(12): 8481-8495, 2020 Dec 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35019618
19.
A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages.
ACS Chem Biol;
14(9): 2055-2064, 2019 09 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31465201
20.
Enantiomerically pure bicyclo[3.3.1]nona-2,6-diene as the sole source of enantioselectivity in BIPHEP-Rh asymmetric hydrogenation.
Chem Commun (Camb);
(41): 5092-4, 2008 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18956032