Detalhe da pesquisa
1.
DNA repair-deficient Xpa/p53 knockout mice are sensitive to the non-genotoxic carcinogen cyclosporine A: escape of initiated cells from immunosurveillance?
Carcinogenesis;
30(3): 538-43, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19136475
2.
Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.
Carcinogenesis;
30(10): 1805-12, 2009 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19696161
3.
Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.
Cancer Res;
67(10): 4648-56, 2007 May 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17510390
4.
MPHASYS: a mouse phenotype analysis system.
BMC Bioinformatics;
8: 183, 2007 Jun 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17553167
5.
Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
Mol Cell Biol;
24(20): 8884-94, 2004 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15456863
6.
Modulation of mammary tumor development in Tg.NK (MMTV/c-neu) mice by dietary fatty acids and life stage-specific exposure to phytoestrogens.
Reprod Toxicol;
23(3): 407-13, 2007.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17229545
7.
Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.
Cancer Res;
65(18): 8166-73, 2005 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16166291
8.
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Cancer Res;
65(9): 3610-6, 2005 May 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15867355
9.
Accelerated aging pathology in ad libitum fed Xpd(TTD) mice is accompanied by features suggestive of caloric restriction.
DNA Repair (Amst);
4(11): 1314-24, 2005 Nov 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16115803
10.
2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair.
DNA Repair (Amst);
4(1): 3-9, 2005 Jan 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15533832
11.
Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice.
Mutat Res;
596(1-2): 143-50, 2006 Apr 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16464479
12.
Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice.
Cancer Res;
62(5): 1338-42, 2002 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11888902
13.
p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
Cancer Res;
64(15): 5118-26, 2004 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15289314
14.
Broad segmental progeroid changes in short-lived Ercc1(-/Δ7) mice.
Pathobiol Aging Age Relat Dis;
12011.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22953029
15.
An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.
Mol Cell Biol;
29(5): 1276-90, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19114557
16.
Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes.
Cancer Res;
68(5): 1347-53, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18316597
17.
Combined oral benzo[a]pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNA repair-deficient Xpa mice.
Carcinogenesis;
24(3): 613-9, 2003 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12663525
18.
Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol.
Toxicol Pathol;
32(2): 192-201, 2004.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15200157