Detalhe da pesquisa
1.
CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation.
PLoS Biol;
16(8): e2005817, 2018 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30157178
2.
Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J Immunol;
200(5): 1853-1864, 2018 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29374075
3.
HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.
J Virol;
92(8)2018 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29386288
4.
Identification and CRISPR/Cas9 Inactivation of the C1s Protease Responsible for Proteolysis of Recombinant Proteins Produced in CHO Cells.
Biotechnol Bioeng;
116(9): 2130-2145, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31087560
5.
Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1.
J Virol;
91(19)2017 10 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28701403
6.
HIV-1 envelope proteins and V1/V2 domain scaffolds with mannose-5 to improve the magnitude and quality of protective antibody responses to HIV-1.
J Biol Chem;
289(30): 20526-42, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24872420
7.
Immune-correlates analysis of an HIV-1 vaccine efficacy trial.
N Engl J Med;
366(14): 1275-86, 2012 Apr 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22475592
8.
Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion.
J Virol;
87(3): 1554-68, 2013 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23175357
9.
Sequences in glycoprotein gp41, the CD4 binding site, and the V2 domain regulate sensitivity and resistance of HIV-1 to broadly neutralizing antibodies.
J Virol;
86(22): 12105-14, 2012 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22933284
10.
Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials.
J Infect Dis;
206(3): 431-41, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22634875
11.
Phylodynamics of HIV-1 from a phase-III AIDS vaccine trial in North America.
Mol Biol Evol;
27(2): 417-25, 2010 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19864468
12.
Protease cleavage sites in HIV-1 gp120 recognized by antigen processing enzymes are conserved and located at receptor binding sites.
J Virol;
84(3): 1513-26, 2010 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19939935
13.
Mutation at a single position in the V2 domain of the HIV-1 envelope protein confers neutralization sensitivity to a highly neutralization-resistant virus.
J Virol;
84(21): 11200-9, 2010 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20702624
14.
Magnitude and breadth of a nonprotective neutralizing antibody response in an efficacy trial of a candidate HIV-1 gp120 vaccine.
J Infect Dis;
202(4): 595-605, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20608874
15.
Novel ring structure in the gp41 trimer of human immunodeficiency virus type 1 that modulates sensitivity and resistance to broadly neutralizing antibodies.
J Virol;
83(15): 7728-38, 2009 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19474108
16.
Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens.
PLoS One;
15(5): e0233866, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32470085
17.
Ethnic differences in the adaptation rate of HIV gp120 from a vaccine trial.
Retrovirology;
6: 67, 2009 Jul 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19604405
18.
Production of a recombinant monoclonal antibody to Herpes Simplex Virus glycoprotein D for immunoaffinity purification of tagged proteins.
J Immunol Methods;
465: 31-38, 2019 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30502324
19.
Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies.
Front Immunol;
10: 1021, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31156622
20.
Ancestral sequences from an elite neutralizer proximal to the development of neutralization resistance as a potential source of HIV vaccine immunogens.
PLoS One;
14(4): e0213409, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30969970