Detalhe da pesquisa
1.
Phase I trial of bortezomib daily dose: safety, pharmacokinetic profile, biological effects and early clinical evaluation in patients with advanced solid tumors.
Invest New Drugs;
36(4): 619-628, 2018 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29094232
2.
In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity.
Drug Metab Dispos;
44(10): 1682-91, 2016 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27504016
3.
Effect of canagliflozin, a sodium glucose co-transporter 2 inhibitor, on the pharmacokinetics of oral contraceptives, warfarin, and digoxin in healthy participants.
Int J Clin Pharmacol Ther;
53(1): 41-53, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25345427
4.
Pharmacokinetics of abiraterone in healthy Japanese men: dose-proportionality and effect of food timing.
Cancer Chemother Pharmacol;
75(1): 49-58, 2015 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25344090
5.
Impact on abiraterone pharmacokinetics and safety: Open-label drug-drug interaction studies with ketoconazole and rifampicin.
Clin Pharmacol Drug Dev;
4(1): 63-73, 2015 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27128004
6.
Food effects on abiraterone pharmacokinetics in healthy subjects and patients with metastatic castration-resistant prostate cancer.
J Clin Pharmacol;
55(12): 1406-14, 2015 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26096139
7.
Impact of cytochrome P450 3A4 inducer and inhibitor on the pharmacokinetics of trabectedin in patients with advanced malignancies: open-label, multicenter studies.
Cancer Chemother Pharmacol;
74(4): 729-37, 2014 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25100135
8.
Mathematical modeling of tumor growth and tumor growth inhibition in oncology drug development.
Expert Opin Drug Metab Toxicol;
8(9): 1057-69, 2012 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22632710