Detalhe da pesquisa
1.
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
Hepatology;
78(5): 1418-1432, 2023 11 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36053190
2.
Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition.
Clin Sci (Lond);
137(21): 1637-1650, 2023 11 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37910096
3.
Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids.
Pediatr Res;
93(6): 1582-1590, 2023 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36151295
4.
Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile.
Arterioscler Thromb Vasc Biol;
42(10): 1262-1271, 2022 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36047410
5.
Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases.
Int J Mol Sci;
24(2)2023 Jan 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36674804
6.
Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.
Diabetologia;
65(5): 763-776, 2022 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35169870
7.
Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.
BMC Med;
20(1): 485, 2022 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36522747
8.
Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorption.
J Lipid Res;
62: 100134, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34626589
9.
Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a.
Hepatology;
72(5): 1638-1653, 2020 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32083759
10.
An early-life diet containing large phospholipid-coated lipid globules programmes later-life postabsorptive lipid trafficking in high-fat diet- but not in low-fat diet-fed mice.
Br J Nutr;
125(9): 961-971, 2021 05 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32616081
11.
A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice.
J Lipid Res;
61(3): 291-305, 2020 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31506275
12.
Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice.
Hepatology;
70(6): 2171-2184, 2019 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31102537
13.
FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements.
J Lipid Res;
60(9): 1547-1561, 2019 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31253637
14.
Epigenetic programming at the Mogat1 locus may link neonatal overnutrition with long-term hepatic steatosis and insulin resistance.
FASEB J;
: fj201700717RR, 2018 May 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29812971
15.
Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease.
Handb Exp Pharmacol;
256: 207-234, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31236687
16.
New insights in the multiple roles of bile acids and their signaling pathways in metabolic control.
Curr Opin Lipidol;
29(3): 194-202, 2018 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29553998
17.
Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.
Gastroenterology;
152(5): 1126-1138.e6, 2017 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28065787
18.
HSPA6 is an ulcerative colitis susceptibility factor that is induced by cigarette smoke and protects intestinal epithelial cells by stabilizing anti-apoptotic Bcl-XL.
Biochim Biophys Acta;
1862(4): 788-796, 2016 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26826017
19.
Hypertrophy induced KIF5B controls mitochondrial localization and function in neonatal rat cardiomyocytes.
J Mol Cell Cardiol;
97: 70-81, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27094714
20.
Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice.
J Lipid Res;
57(8): 1455-64, 2016 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27313057