Detalhe da pesquisa
1.
Abolishing ß-arrestin recruitment is necessary for the full metabolic benefits of G protein-biased glucagon-like peptide-1 receptor agonists.
Diabetes Obes Metab;
26(1): 65-77, 2024 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37795639
2.
Adaptive infusion of a glucagon-like peptide-1/glucagon receptor co-agonist G3215, in adults with overweight or obesity: Results from a phase 1 randomized clinical trial.
Diabetes Obes Metab;
26(4): 1479-1491, 2024 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38229453
3.
100 years of glucagon and 100 more.
Diabetologia;
66(8): 1378-1394, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37367959
4.
The postprandial secretion of peptide YY1-36 and 3-36 in obesity is differentially increased after gastric bypass versus sleeve gastrectomy.
Clin Endocrinol (Oxf);
99(3): 272-284, 2023 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36345253
5.
Tripeptide gut hormone infusion does not alter food preferences or sweet taste function in volunteers with obesity and prediabetes/diabetes but promotes restraint eating: A secondary analysis of a randomized single-blind placebo-controlled study.
Diabetes Obes Metab;
25(6): 1731-1739, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36811311
6.
Genetic and biased agonist-mediated reductions in ß-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
J Biol Chem;
296: 100133, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33268378
7.
Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.
PLoS Biol;
17(8): e3000097, 2019 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31430273
8.
Acylation of the Incretin Peptide Exendin-4 Directly Impacts Glucagon-Like Peptide-1 Receptor Signaling and Trafficking.
Mol Pharmacol;
100(4): 319-334, 2021 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34315812
9.
Differential effects of bile acids on the postprandial secretion of gut hormones: a randomized crossover study.
Am J Physiol Endocrinol Metab;
320(4): E671-E679, 2021 04 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33459181
10.
Safety and efficacy of an extended-release peptide YY analogue for obesity: A randomized, placebo-controlled, phase 1 trial.
Diabetes Obes Metab;
23(7): 1471-1483, 2021 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33606914
11.
Imperial Satiety Protocol: A new non-surgical weight-loss programme, delivered in a health care setting, produces improved clinical outcomes for people with obesity.
Diabetes Obes Metab;
23(1): 270-275, 2021 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32991078
12.
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.
Int J Mol Sci;
21(21)2020 Nov 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33182425
13.
Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial.
Lancet;
389(10081): 1809-1820, 2017 May 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28385352
14.
Commentary on "The road to reliable peptide assays is paved with good guidelines".
Clin Endocrinol (Oxf);
98(6): 763-765, 2023 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36915993
15.
A second dose of kisspeptin-54 improves oocyte maturation in women at high risk of ovarian hyperstimulation syndrome: a Phase 2 randomized controlled trial.
Hum Reprod;
32(9): 1915-1924, 2017 09 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28854728
16.
Insights into the role of neuronal glucokinase.
Am J Physiol Endocrinol Metab;
311(1): E42-55, 2016 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27189932
17.
Subcutaneous infusion of kisspeptin-54 stimulates gonadotrophin release in women and the response correlates with basal oestradiol levels.
Clin Endocrinol (Oxf);
84(6): 939-45, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26572695
18.
Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.
Angew Chem Int Ed Engl;
55(19): 5865-8, 2016 05 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27059784
19.
Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults.
Gut;
64(11): 1744-54, 2015 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25500202
20.
What Can We Learn From Mouse Models About Bile Acid-Mediated Changes After Bariatric Surgery?
Gastroenterology;
157(1): 4-8, 2019 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30930023