Detalhe da pesquisa
1.
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Nature;
591(7850): 451-457, 2021 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33561864
2.
Modeling Heartland virus disease in mice and therapeutic intervention with 4'-fluorouridine.
J Virol;
98(4): e0013224, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38511932
3.
ATI-2173, a Novel Liver-Targeted Non-Chain-Terminating Nucleotide for Hepatitis B Virus Cure Regimens.
Antimicrob Agents Chemother;
64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32540975
4.
Analysis of the Potential for N4-Hydroxycytidine To Inhibit Mitochondrial Replication and Function.
Antimicrob Agents Chemother;
64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31767721
5.
Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance.
J Virol;
93(24)2019 12 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31578288
6.
Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.
Proc Natl Acad Sci U S A;
114(5): E811-E819, 2017 01 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28096399
7.
Simple In Vitro Assay To Evaluate the Incorporation Efficiency of Ribonucleotide Analog 5'-Triphosphates into RNA by Human Mitochondrial DNA-Dependent RNA Polymerase.
Antimicrob Agents Chemother;
62(2)2018 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29180528
8.
Analysis of Ribonucleotide 5'-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays.
Antimicrob Agents Chemother;
61(3)2017 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27993851
9.
The prophylactic and therapeutic efficacy of the broadly active antiviral ribonucleoside N4-Hydroxycytidine (EIDD-1931) in a mouse model of lethal Ebola virus infection.
Antiviral Res;
209: 105453, 2023 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36379378
10.
4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Science;
375(6577): 161-167, 2022 Jan 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34855509
11.
4'-Fluorouridine is a broad-spectrum orally efficacious antiviral blocking respiratory syncytial virus and SARS-CoV-2 replication.
bioRxiv;
2021 May 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34031658
12.
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Sci Transl Med;
12(541)2020 04 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32253226
13.
The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection.
Antiviral Res;
171: 104597, 2019 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31494195
14.
Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.
Sci Transl Med;
11(515)2019 10 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31645453
15.
Lassa and Ebola virus inhibitors identified using minigenome and recombinant virus reporter systems.
Antiviral Res;
136: 9-18, 2016 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27771389